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India: What are things that make Indians sad?

This post shared by Sachin Tendulkar (cricketer) made me sad today. Please read the full description before hating me !Disclaimer :I am also a big fan of Sachin and have always prayed and even fasted sometimes for him !This post is not intended for Sachin only but for every MP who takes Indian Parliament for granted and gets huge salary and benefits which come directly from our Taxes !A new movie “ Sachin: A Billion Dreams (2017 movie) " based on the life of Indian cricket icon and living legend Sachin Tendulkar is going to release on 26 May, 2017 and as you can see in the picture above that Sachin is meeting our Hon'ble PM Narendra Modi Ji for promoting his picture. But he doesn't have time to attend Parliament session. Lets get to some facts.There are 12 nominated members in the Rajya Sabha and Sachin is one of them since 2012. Former cricketer Sachin Tendulkar and actress Rekha are the worst performers in attendance in the Rajya Sabha among the 12 nominated members.Attendance in the House :Tendulkar has attended only 23 of the 348 days since his nomination in 2012 and in terms of percentage that accounts to a meagre of only 6.67%.Participation in Debates :Here Sachin has scored a duck for the last five years which is opposite to his cricket career. He has not participated in Parliament in a single debate till nowExpenditure Incurred on Salary & AllowancesAs of now total expenditure incurred on Sachin is Rs 58.8 lakhs since 2012 and if in terms of expenditure per day of attendance then this amounts to Rs 2.56 lakh per day. Each MP is entitled to the following,Salary (Rs 50000 per month)Constituency Allowance (Rs 45000 per month)Office Expense Allowance (Rs 15000 per month)Travel & Daily Allowance (TA/DA) (Variable)Complete details of expenditure incurred on every Rajya Sabha Member is available here on this website. http://164.100.47.5/NewMembers/mp_income_display.aspxRead more at:http://economictimes.indiatimes.com/articleshow/58124244.cms?utm_source=contentofinterest&utm_medium=text&utm_campaign=cppstSachin overtakes Rekha in Rajya Sabha AttendanceDear Sachin,We all really love you and there is no denying to this fact we are definitely going to watch your movie. But a humble request , please respect Indian Parliament and give your precious time there also and if you cannot do this then please vacate the seat for any other suitable candidate.Wishing you good luck for your upcoming movie !With Love,Your Billion FansEdit 1 :I must mention that inspite of his low attendance in Parliament he has done his duty well outside the parliament. He has adopted two villages one in Andhra and second in Maharashtra which are doing very well. The conditions of these villages have improved a lot and now they have got access to basic facilities. The fact that he adopted the villages while extremely commendable, does not in any way justify the gross ignorance of his responsibility. One does not balance the other.People are commenting about his charity work. My above post does not criticize Sachin for his cricket neither for his Charity work. He is a very very good cricketer and a good human, have done a lot of charity and I appreciate that. But his good doing can’t simply coat his negligence in another important work entrusted on him.Many people are also commenting that he is a nominated member and not the elected member. He has not asked for this but Govt of India has honored him this title. My point is that if he knew that he will not be able to attend the parliament and take part in its proceedings then he should have respectfully denied this duty and passed to someone else. By nominating members to Rajya Sabha, the State not only recognizes their merit and confers honour on them, but also enables them to enrich the debates by their expertise and knowledge that they have in different areas. Nominated members enjoy all powers, privileges and immunities available to an elected member of Parliament. They take part in the proceedings of the House as any other member.Edit 2 : Thanks all for your upvotes. Never expected such a huge response. You can follow me on Quora at Ankit Sharma.

Why has the link between the Zika virus and microcephaly only appeared in Brazil in 2015?

BecauseZika was historically rarely associated with human disease outbreaks, with only one reported cluster of 7 human cases in Indonesia in 1981 (1).Human Zika virus was sporadically isolated in East and West Africa in the absence of epidemics (2, 3, 4).Association between Zika and congenital microcephaly was first observed only in Brazil in October 2015, shortly after the country first confirmed Zika virus cases in May 2015.Subsequently, French Polynesia also reported a similar link (5).Right now, there's a spatio-temporal, not causation, link between Zika and microcephaly cases in Brazil (see figures below from 5) and in French Polynesia.According to a Pan American Health Organization (PAHO) Epidemiological Alert issued on 1 Dec, 2015 (6), 'As of 30 November 2015, 1,248 cases (99.7/100,000 live births) of microcephaly, including 7 deaths, have been reported in 14 states of Brazil, which are under investigation (3). In 2000, the prevalence of microcephaly in newborns in Brazil was 5.5 cases/ 100,000 live births and in 2010 it was 5.7 cases / 100,000 live births. This data demonstrates a twentyfold increase in comparison to the rate observed in previous years. The data was obtained from the Live Births Information System (Sinac, per its acronym in Portuguese) which captures epidemiological data related to pregnancy, births and congenital malformation, in addition to the socio-demography of the mothers.' (According to PAHO, Sinac is a universal system, which captures information on births in the entire national territory of Brazil. Available at: DATASUS).Zika virus outbreaks first began to be reported in Polynesia in 2007.After that original 1981 report (1), Yap in the Federated States of Micronesia (estimated population ~11000) experienced a Zika virus outbreak in 2007 (7, 8), where for the first time using an originally designed PCR to detect it, Zika virus RNA was found in acute phase disease serum samples. A much smaller population, this outbreak reported no spike with congenital microcephaly, an easily identifiable condition. Why? Was it missed or was it absent? Or is it linked to frequency, i.e., more infected people, higher the chances of congenital microcephaly? Not yet known.Compared to the 2007 Micronesian outbreak, a much higher number of people were infected with Zika virus during a 2013 outbreak in French Polynesia, where by week 51, there were a total of 5895 suspected Zika virus cases (9).Recently, French Polynesia also reported a spatio-temporal link between Zika and congenital microcephaly, 'On 24 November 2015, the health authorities of French Polynesia reported an unusual increase of at least 17 cases of central nervous system malformations in foetuses and infants during 2014–2015, coinciding with the Zika outbreaks on the French Polynesian islands. These malformations consisted of 12 foetal cerebral malformations or polymalformative syndromes, including brain lesions, and five infants reported with brainstem dysfunction and absence of swallowing. None of the pregnant women described clinical signs of ZIKV infection, but the four tested were found positive by IgG serology assays for flavivirus, suggesting a possible asymptomatic ZIKV infection. Further serological investigations are ongoing. Based on the temporal correlation of these cases with the Zika epidemic, the health authorities of French Polynesia hypothesise that ZIKV infection may be associated with these abnormalities if mothers are infected during the first or second trimester of pregnancy' (5). Why in 2015 but not in 2013? What's different? Are 2015 Brazilian and French Polynesian Zika virus isolates different from the 2007 Yap State outbreak, different as in greater trans-placental transfer? Not yet known.Prior to the Brazilian Ministry of Health announcement (10), there's no report in the scientific literature suggesting such a link, only serologic evidence and sporadic virus isolation from humans and mosquitoes in Africa and Asia (see figure below from 11) while the 2007 Micronesian Yap State Zika virus outbreak was the first time it was detected outside Africa and Asia.In order to conclude that Zika and only Zika caused these cases of congenital microcephaly, investigations need to carefully rule outOther infections, particularly Vertically transmitted infectionGenetic risk factorsMaternal exposure to toxins/chemicalsMaternal consumption of potentially teratogenic drugsthough the last three are unlikely to explain the sudden spike in 2015.The Brazilian Ministry of Health reported the presence of Zika virus RNA in amniotic fluid samples of two pregnant women with fetal microcephaly in Paraiba state in 2015 (12). This suggests trans-placental Zika virus transfer, bringing us closer to a causal link.Meantime, as of Dec 2015, Colombia reported averaging >1000 Zika virus cases per week for over a month (13). This may unfortunately mean that 2016 births in Colombia will show if Zika and congenital microcephaly link is generalizable (14). A causal link would be scary since this is a mosquito-borne disease, unlike most vertically transmitted infections, i.e., chances of getting infected are not in the pregnant mother's full control.Bibliography1. Olson, J. G., and T. G. Ksiazek. "Zika virus, a cause of fever in Central Java, Indonesia." Transactions of the Royal Society of Tropical Medicine and Hygiene 75.3 (1981): 389-393.2. Simpson, D. I. H. "Zika virus infection in man." Transactions of the Royal Society of Tropical Medicine and Hygiene 58.4 (1964): 339-348.3. Moore, D. áL, et al. "Arthropod-borne viral infections of man in Nigeria, 1964-1970." Annals of tropical medicine and parasitology 69.1 (1975): 49-64.4. Fagbami, A. H. "Zika virus infections in Nigeria: virological and seroepidemiological investigations in Oyo State." Journal of Hygiene 83.02 (1979): 213-219. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2129900/pdf/jhyg00044-0020.pdf5. Microcephaly in Brazil potentially linked to the Zika virus epidemic. European Centre For Disease Prevention And Control, 24 Nov, 2015. http://ecdc.europa.eu/en/publications/Publications/zika-microcephaly-Brazil-rapid-risk-assessment-Nov-2015.pdf6. PAHO Epidemiological Alert, 1 Dec, 2015. http://www.paho.org/hq/index.php?option=com_docman&task=doc_view&Itemid=270&gid=32405&lang=en7. Lanciotti, Robert S., et al. "Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007." Emerging infectious diseases 14.8 (2008): 1232. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600394/pdf/08-0287_finalR.pdf8. Duffy, Mark R., et al. "Zika virus outbreak on Yap Island, federated states of Micronesia." New England Journal of Medicine 360.24 (2009): 2536-2543. http://www.nejm.org/doi/pdf/10.1056/NEJMoa08057159. Cao-Lormeau, Van-Mai, et al. "Zika virus, French polynesia, South pacific, 2013." Emerging infectious diseases 20.6 (2014): 1085. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036769/pdf/14-0138.pdf10. PAHO Epidemiological Alert, 17 Nov, 2015. http://www.paho.org/hq/index.php?option=com_docman&task=doc_view&Itemid=270&gid=32285&lang=en11. Hayes, Edward B. "Zika virus outside Africa." Emerging infectious diseases 15.9 (2009): 1347. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819875/pdf/09-0442_finalS.pdf12. Ministério da Saúde (Brazil). Microcefalia - Ministério da Saúde divulga boletim epidemiológico [Internet]. Brasília: Ministério da Saúde; 2015 [updated 2015 Nov 17; cited 2015 Nov 17]. Available from: Ministério da Saúde divulga boletim epidemiológico13. Oubreak News Today, Robert Herriman, Dec 19, 2015. Colombia averaging more than 1000 Zika cases weekly for the past month14. Oubreak News Today, Robert Herriman, Dec 20, 2015. Colombia to look at Zika-microcephaly linkThanks for the A2A, Christian Dechery.

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