Patient Profile Template: Fill & Download for Free

I'm not quite sure why you'd want one if you're unable to understand the jargon used on it. You should just know that the front page of a medical file that contains a person's psychiatric and medical histories (template). These vary from facility to facility or between networks. They are protected by HIPPA and are never shared unless it's with a doctor, nurse, guardian or the patient themselves.

Sit down and settle in, this is going to be long read. This answer is probably best viewed on a non-mobile browser. :-)===============~ BACKGROUND ~===============To understand HIV medication, you must first understand the 6 crucial steps that HIV needs to complete in order to replicate and spread. In order, they are:Binding and fusion: HIV binds to either or both of two cell receptors known as CCR5 (typically in initial stages of infection) and CXCR4 (often in later stages) in order to enter the cell. HIV is surrounded by a lipid envelope that allows it to fuse with the target cell's membrane, releasing the virus's core contents into the cytoplasm.Reverse transcription: HIV's genetic code is RNA-based, so its reverse transcriptase enzyme generates a DNA template.Integration: The DNA template is then integrated into the host cell's genome.Transcription: The host cell's protein machinery transcribes and translates mRNA based on the integrated DNA template.Protease cleavage: HIV proteins are initially made in large chains known as poli-proteins, which are cleaved into their functional pieces by proteases.Assembly and release: New virions assemble at the cell membrane and bud from the cell surface.================================~ DRUG CLASS 1: ENTRY INHIBITORS ~================================CCR5 antagonists prevent the first binding step, stopping the virus from entering any cells. The problem is that this is only effective for patients whose variant of HIV solely relies on the CCR5 receptor for virility, so if a tropism test reveals a CXCR4-dependent virus, this option is not used.Maraviroc is the only FDA-approved drug in this class.Common side effect (CSE): hepatotoxicity (liver problems)Fusion inhibitors allow the virus to bind initial receptors, but prevent the next step of fusion between the viral and cellular membranes.Enfuvirtide is the only FDA-approved drug in this class, and is given through subcutaneous injections.CSE: Injection site inflammation/redness in 90% of patients, usually mild.================================================~ DRUG CLASS 2: REVERSE TRANSCRIPTASE INHIBITORS ~================================================Nucleoside analogue reverse transcriptase inhibitors (NRTIs) compete with natural nucleotides, leading to premature DNA chain termination.Drugs: Abacavir, Didanosine, Emtricitabine, Lamivudine, Stavudine, Tenofovir, ZidovudineCSE: Mitochondrial toxicity from inhibition of the enzyme responsible for mitochondrial DNA synthesis.Non-nucleoside reverse transcriptase inhibitors (NNRTIs) bind to the reverse transcriptase enzyme, inhibiting its function.Drugs: Delavirdine, Efavirenz, Etravirine, NevirapineCSE: Rash, hepatitis====================================~ DRUG CLASS 3: INTEGRASE INHIBITORS ~====================================These inhibit incorporation of viral DNA into the host's genome.Raltegravir is the only FDA-approved drug in this class.CSE: muscle damage/problems===================================~ DRUG CLASS 4: PROTEASE INHIBITORS ~===================================PIs inhibit viral proteases from cleaving viral poli-proteins into their functional bits, preventing assembly of the virus.Drugs: Atazanavir, Fosamprenavir, Darunavir, Indinavir, Lopinavir, Nelfinavir, Saquinavir, TipranavirRitonavir is a PI that is frequently used in low doses for its interesting effect of preventing metabolism of other PIs--increasing their efficacy.CSE: Many possible--nausea, vomiting, diarrhea, hepatitis, etc.=======================~ TREATMENT REGIMENS ~=======================Treatment regimens vary widely based on the patient, the progression of the disease, the strain of HIV, etc. Broadly speaking, initiation of therapy in treatment-naive patients often begins with one of the following 3-drug combos:2 NRTIs + 1 PI (usually boosted with ritonavir)2 NRTIs + 1 NNRTI2 NRTIs + 1 integrase inhibitorThe idea is to prevent further spread of the virus in the patient with a cocktail to prevent easy resistance mutations. Some of the many things to consider to individualize the treatment for each patient:patient preferencetoxicity profilechild-bearing potential (women)strain's baseline resistance(s)does the patient have other conditions that require treatment? (drug interactions)Key to the regimen are regular check-ups which evaluate adherence to treatment, potential psychological concerns, side effects/complications, resistances, etc. Patients are counseled on prevention of HIV transmission and opportunistic infections, as well as other health changes that might be appropriate.~~~~~This answer was written June 15, 2010, and was developed from course material given in my curriculum. None of this information should be taken as professional medical advice, and is provided "as is" for informational purposes only, as there are a great many details on this subject that I have not included here, whether by ignorance or by choice. I've made this highly-condensed summary as accurate and up-to-date as possible, but realize that HIV/AIDS research is a very active field and the above information could change at any time. If there is anything you would like further clarification on, leave a comment and I'll do what I can.Cheers,~Jae

Please forgive me for my sins, as I have tried to create a picrew purely based on my common knowledge of children’s dress up games and I stepped into this mess with no knowledge of the Japanese language.When I first googled the website, I thought it would be in English since so many English speakers use this site but I was met with Japanese. Which meant that I had to do everything based on colors. Luckily, since I am a profession veteran gamer I know that green means save and red means discard.I searched a video explaining me how to make a picrew but, when I saw that it was over half an hour long I decided to stick with my original plan of pressing buttons and see what happens (I mean, how has that ever brought problems along?). I lost my first template because I didn’t save it but, I did copy the link for my second attempt.I tried to make it as accurate as possible but in the end, I couldn’t find any clothes that properly projected what I am wearing right now. I wasn’t satisfied yet since I wanted to find that overused template that everyone has as their profile picture so I could also try that out. Solution to my problem: Just google picrew template, go to images and steal it from there. This one is way more accurate as to what I’m wearing in the moment mostly because I found out how to change the colors, I looked like a pirate finding their golden treasure when I saw that the paintbrush existed.(okay, maybe I don’t have the flag right now but, I do have an agender flag heart hanging on my door.)If you have been following me for a little longer you might know that I really want to change my overall appearance to a more androgynous one and in real life, I’m working towards that goal as secret as possible since my parents still don’t know how I feel and my mother surely wouldn’t accept me (especially after what happened yesterday evening). So I made a character I wish to look like:Take that society, guess my gender now huh? Well, I only have to wait 5 more years until I can finally take that type of style but patience is the key to success they say. Guess I have to be patient and wait for my time then.Enjoy your day/night :3