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PDF Editor FAQ
What are some rare mutations in modern humans?
Progeria is a rare, fatal genetic condition which accelerates the aging process in children.Within the first two years of life, the signs of aging include growth failure, loss of body fat and hair, aged-looking skin, hip dislocation, heart disease and stroke. Children with Progeria die of atherosclerosis (heart disease) at an average age of fourteen years.[1]South African artist called DJ Leon Botha is believed to be one of the longest living survivors of the condition, dying at the young age of 26.He inspired many like him and is known for his positive attitude towards life. In Leon's words —“Just like any other human being, I don't like to be reduced to a condition or a statistic and I sure as hell won't end up on one of the photos to be paraded on websites to inspire pity and s--t ... wrong guy."Footnotes[1] About Progeria | The Progeria Research Foundation
Is it theoretically possible to stop or slow down aging?
Slowing it down, even a little bit, is very difficult, and stopping it is definitely impossible. But paradoxically, reversing it is relatively easy. SENS Research Foundation is spearheading the development of medicines to do that. See SRF Home | SENS Research Foundation for details.
What technologies could have the most impact on extending human life?
Eliminating any single disease will give at most a few years - the only option for significant extension is postponing aging itself, i.e. the accumulation of molecular and cellular damage. The most feasible way to do that is to periodically repair the damage, which is what SENS Research Foundation are working to do. Improved communication is always good, but ultimately the one thing that's needed far more than anything else is more funding (for the entire effort, not only for SENS Research Foundation). I estimate that the relevant research is going only about 1/3 as fast as it could with ten times more money. (Our current budget is about $4M/year.)
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