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Researchers at UCSD have validated an EEG test to study Schizophrenia.Paper 1 : Cortical substrates and functional correlates of auditory devianceprocessing deficits in schizophreniaPaper 2: Validation of mismatch negativity and P3a for use in multi-site studies of schizophrenia: Characterization of demographic, clinical, cognitive, and functional correlates in COGS-2In experiments, UC San Diego scientists and colleagues with the Consortium on the Genetics of Schizophrenia monitored volunteers’ electrical brain activity patterns as they listened to a sequence of beeps that occasionally included a discordant prolonged beep. The lengthier beeps were one-twentieth of a second longer than the standard beeps and occurred roughly 10 percent of the time.A total of 1,790 people were tested at five sites nationwide as part of a National Institutes of Health-funded study to unravel the genetic basis of schizophrenia. Nine-hundred and sixty-six were schizophrenia patients; 824 were healthy control subjects.The EEG data were analyzed for two auditory processing metrics. One is known as mismatch negativity (MMN). Measured in microvolts, MMN represents the difference between the brain’s response to the expected stream of beeps and its response to the singular, different ping. The other, called P3a, is a measure of the electrical energy emitted by the brain as it automatically shifts attention to the longer beep.People with schizophrenia were consistently shown to have reduced MMN and P3a relative to those without the disease, suggesting they had a muted ability to detect and direct their attention to the discordant beep.In the second study, researchers showed that measures of MMN and P3a were associated with the severity of a patient’s symptoms and their day-to-day real-world functioning.Specifically, in a comparison of MMN and P3a measurements from 42 patients with schizophrenia and 47 non-psychiatric comparison subjects, scientists showed that differences in these auditory processing metrics accounted for approximately half of the variance in the severity of patients’ symptoms and their ability to perform tasks necessary for real‐world functioning.The two studies further validate the ability to measure MMN and P3a with only one EEG electrode placed on the front of the scalp, meaning that the EEG testing can be conducted outside of academic research laboratories.** The MMN is the negative component of a difference wave between responses to standard and deviant events embedded in an oddball paradigm. This negative response, of about 5 μV maximum peak, is distributed over fronto-central scalp locations

3 months ago I attended a 10 day Vipassana meditation retreat. A lot of people asked me to post my experience. I was a little uncomfortable as I wanted to see if the changes are lasting before posting them. Here is something that seems to be permanent atleast for the past 3 months.I now consistently get up at 2:45 AM without an alarmI consistently meditate 3 AM-4 AMI consistently workout 4 AM-5 AMI sleep by 8:30-9 PM and my sleep score is consistently 93% and above.I also fast 20hours and eat 2 meals 1:30 PM and 5:30 PM and don’t eat after sunset though I used to fast even before Vipassana.All the above has become completely automatic and I don’t need any motivation or system to follow them.This is me getting my functional MRI and PET Brain scan done after Vipassana to compare with my Pre Vipassana scan to see any structural changes to my brain. I have one more due next month to see the 3-month changes after which I will post results. Huge thanks to NIMHANS Hospital for sponsoring the scans. There is enough research suggesting that Vipassana meditation contributes to increased occipital gamma power related to enhanced sensory awareness. This is consistent with the aim of Vipassana meditation to reduce cognitive and emotional reactivity, the state effect of reduced P3a amplitude to distracting stimuli reflects decreased automated reactivity and evaluative processing of task-irrelevant attention-demanding stimuli AKA FocusVipassana Meditation has been life-changingUpdate: it’s 5 months now and the habits are stronger than ever.Update: Wow 1200+ upvotes and 120K views in less than 4 days!!!. Really grateful to you guys! If I can motivate even 1 person to meditate then my purpose of this post is achieved.Due to the COVID-19 situation, the PET SCAN dept at NIMHANS is closed. I am eagerly waiting to see my scan results when they reopen. Thanks to all of you for your keen interest, I will share the results.Tip: You will automatically get updated when I share my results if you upvote my answer.Some people have mentioned that it is very difficult to take 10-day leave from work to attend the retreat. I would like to share that few states allow for 10 days' leave with pay to attend Vipassana. You can check the Govt. Circular here. Government CircularsI tweet regularly on topics of Finding the meaning of life, Meditation, and Fasting. Please follow me here supratim dasgupta and I will follow you back!.

MAVIC’s camera sensor is better than P3A. But i think P3's gimbel is more stableThis is MAVICThis is P3A