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PDF Editor FAQ

What is paroxysmal nocturnal hemoglobinuria?

Let me build a picture for you.A man, comes to his Urologist and complains of occasional coca cola colored urine some MORNINGS.Further, he reports that he gets tired easily… poor fellow. :PThe urologist notes:PallorFever (say 39 degree celsius)Bleeding gums (possibly but not specific)EcchymosisThen he asks for some lab results…On the next visit the patient brings the urologist the lab results…On urine analysis: you find Hemoglobin in urine (Hemoglobinuria) plus hemosiderin in urine (Hemosiderinuria)In blood, free hemoglobin levels are found raised along with haptoglobin. (Reticulocyte count was also raised)Direct Antiglobulin test was negative.Flow cytometry for CD 55 was also negative.CD 55 is DECAY accelarating factor. If it is not there, as in our case, the complement proteins are not degraded. CD 55 would have helped the poor RBC if complement got attached to it by mistake.But since it is not there, Complement attacks the poor RBC particularly in the night time.WHY night time ?In nights, most guys and gals are sleeping. (Except the medicos, for that matter.)We do shallow breathing while we sleep. Carbon Dioxide levels in blood are higher as compared to when we are awake. This lowers the pH. It makes the blood relatively more acidic. This augments the activation of complement.By the way, this patient will die in 10–12 years. Unless he undergoes bone marrow transplantation. The cause of death is most likely gonna be thrombosis.

What is the admission process in AIIMS Rishikesh after reporting?

Ahh it's pretty much the same in all AIIMS.They'll have the reporting candidates and their parents assemble in a conference room. After some waiting they'll send you guys for the medical checkup.You'll be enrolled in the OPD and then pulse, BP, BMI, urine analysis, ECG, and few other tests will be conducted. They will provide you with a medical certificate.Then there will be the document verification process. You have to carry all your original documents with you.In case you're depositing a demand draft, they'll receive self atttested photocopies(Xerox) of the relevant documents and check the originals.In case you're submitting your originals well then no need for photocopies.You'll have to deposit the admission fees in the partnering bank of the institute and return with one receipt that you'll submit to the office and another one that you'll keep for yourself.Based on whether you're taking admission/upgrading in the next round, there will be some paperwork. You'll be provided with anti-ragging and acknowledgment sample forms to be submitted in an affidavit form later on before the commencement of classes.Finally, if you're taking admission, there will be the hostel allotment process.Best wishes,KD.

What are some weird things that an MBBS student must learn to do?

There are many things in MBBS that a normal individual will find weird but as a medical student you have to get used to them..So as every year passes you become more casual to various weird things like:In first year- you become habitual to the smell of formalin that is used to preserve cadevers in dissection hallYou are ok with the self harm as for physiology practical you have to prick yourself with a Lancet to collect blood for DLC and TLCWhen the end of first year comes you become so used to of naked dead bodies that you can even enjoy snacks or can giggle in front of the bodies without hesitationAnd in biochemistry practical you have to smell the urine while performing urine analysisAnd above all you develop a talent of sleeping with bones around your bedIn second year - you become habitual of sleeping during your lectures.. playing games on mobile phone during lecture.. I used to do all these things during my pathology lectures and that was absolute funYou learn about collection of stool samples, urine samples, sputum samplesIn forensic medicine you are taught to write a post mortem reportIn third year- you have to develop communication skills so that you can get a proper history from a patient who is a complete stranger to youDuring history taking you've to ask very personal questions to a patient without any hesitation like the type of contraception is being used by the couple, you've to ask about their bowel bladder habits, about their alcohol drinking and smoking, in female patients you've to enquire about their menstrual cycleIn final year- you become so usual to naked humans that you don't even hesitate while touching genitals during examination of scrotal swelling or hernia examinationIn obgy postings you have to do pervaginal examinationAnal examination with finger inside anal canalIn medicine ward you've to consider yourself immortal as you are highly susceptible to various contagious diseases like tuberculosis etc.And the list can go on on as there are many things that are weird for normal people and casual for a medico..Btw these 5.5 years in a medical school make you shameless and non hesitant..So keep your spirits high and keep on learning!!

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