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What would doctors do in a world without diseases, accidents or natural calamities?

It’s funny you should ask that, because this actually happened a long time ago, when I was a young neurologist in Philadelphia. The entire world was completely free of disease and injury, but we still needed doctors everywhere.I mean it happened in the future, but I saw it a long time ago. No, the incident I’m talking about happened in the past… I mean… all right, okay, I know what that smile means, you think it’s my Alzheimer’s talking, don’t you?Well, for once, this old man has proof. You see that file? No, not that one, yes, no, ah, that one! Play it.<beep><static><time stamp initiates>State your name for the record, please.My real name is Marcus Arven Nitin. But your genetic directory will show that my name is Asher Nitin.Are you saying that you are not the person listed on the genetic directory?Yes.<murmurs, someone coughs>We will return to that. Sir, let me begin by stating the facts for your benefit as well as that of the investigation committee.By all means, major.Three days ago, at 10:20 a.m. Eastern Daylight Time, a massive explosion occurred in central Boston, leveling two entire city blocks and resulting in massive loss of life and damage to property.NEST teams determined the explosion was non-nuclear in nature and found at the center of the detonation a crater 170 meters wide and 200 meters deep.At the bottom of the crater was this… structure, ah, on the screen.<murmurs, scratching of pens(?)>The outer shell was badly damaged, but thermal imaging revealed a signature within. We cut open the outer shell and found an inner shell with a hatch set in it. Beside the hatch were engraved instructions in English and Mandarin detailing the opening procedure for the hatch and a schematic explaining the contents. Upon opening the hatch, we found you strapped to a chair surrounded by what we presume to be life support systems. You were unconscious, mildly febrile, and on both feet, your little toe was swollen and red.I know. And I’d ask you where we are now, but I’m guessing you’d say that you cannot disclose that information for security reasons/Yes, sir, for security reasons.<subject laughs lightly>Then we’d better get down to it. I know how tacky this will sound. Half of you will pinch yourself ten seconds from now because you won’t believe this is real. The other half will suppress smiles because this will sound so tacky, but here it is, plain and straight: I am from the future and I have been sent to warn you.<murmuring, chair scrapes><coughing>Do you have proof to back this claim?Yes. In my habitat in the survival system I was sent back in, you will find to the left of my harness a safe marked 6-EVIDENCE. Your EOD teams and analysts are still trying unsuccessfully to open them but by now have determined there are three objects inside.I’m giving you the code to the safe. It is this… draw this shape in the air… like this… in front of the safe five times and it will open. Inside you will find a bowl, a spoon and a pen. Chemically analyze all of them. They’ve been made of materials that do not exist yet.Isn’t there some rule against bringing back technology from the future? If we reverse-engineered it, wouldn’t it..If you reverse-engineered it, you’d gain five years. If you don’t, the plastic in that pen will anyway exist five years from now, the metal in the spoon and the ceramic in the bowl in four.We figured there were only two ways you’d believe I am who I claim to be.One: the technology, so we included objects that would disrupt the timeline as little as possible. Everything else in the craft is made from materials currently available.Two: my code.Clarify that for me sir.My genetic code is Asher Nitin’s. The records will show he died in 2046 ACE. And yet here I am, with his exact code in my cell nuclei. Once you’re done checking your directory for an error, you will conclude the only other way for that to happen is via technology that allows us to replace the entire genetic code.But there’s more. My actual code is still on me. We re-coded all the cells in my body except for the ones toward the tip of my little toes. My symptoms are because I’m running an…Autoimmune infection?…yes. You took a tongue swab the first time. Now take a biopsy from each of my small toes. Compare the code you get with every other entry in your registry. You won’t get a match. That should prove specificity and accuracy of technology, I think. Listen, captain, I’m…It’s Major, sir.…major, I’m tired, it’s the fever, so how about I give you the short version? I know nothing I say will carry any weight until you have finished verifying both my proofs. And that can take a week.Very well, sir. Make your statement.I have been sent to warn you this: do not scrap NASA’s <static> and put the funding into the WHO’s <static>.I don’t know what that means, sir. Are those science programs?<subject laughs>I know you don’t. But that man, and the man next to him, whispering in his ear, he’s stopped now, do. They’re in charge of it, they think it will be the next big multi-industry science mission of the century, after going to the moon. And the problem is they are right. It will work.And?And you will turn Earth into heaven, and then heaven into hell.You can’t see it now, but you will. It will set off a series of discoveries that will earn it’s participants a Nobel in Medicine, and their successors another three Nobel Prizes, in Medicine, of course, and one incredible guy two Nobel Prizes, one in Medicine and one for Peace. And everything will go to hell in a hand-basket from there on, because one century later…By 2037 ACE…Genetic engineering will identify all defective genes in the human genome and code healthy versions of the same genes.Scientists in biotechnology and virology will collaborate to create the first viral engineers. Viral engineers will be a step above attenuated vaccines. These are benign viruses that will be capable of invading individual cells and replacing defective sections of DNA with normal versions of the same genes.But the problem will be the cost. These things will be prohibitively expensive. So you’re going to try to cut costs by reusing the same viruses over and over again. Distributing them through the body is simple. Collecting them won’t be that easy.Advances in nanotechnology will result in nanobots small enough to enter a bloodstream and inject viral engineers in distributed doses throughout the body, then collect them and assemble in the urinary tract so they can be collected in the urine.You’ll tinker and adjust till the process becomes ridiculously cheap. And you’ll start the IDVP- the Intrinsic Disease Vaccination Program. And just like that, within three generations, 80% of all autoimmune diseases, 30% of all forms of cancer, 100% of all metabolic diseases and 50% of all neuropsychiatric diseases will disappear.30% of the population will resist, on grounds that this is tinkering with original design. You will call them a lot of things, none of them complimentary. Some you debate into submission, some you will bribe and coerce, some you will force, and some will kill themselves. That will trigger a PR war, and in the end you will create the genetic registry you’re using today, to identify the unmodified populace. It will sound like Nazism, except that they themselves will insist on it. Over time, their numbers will decrease and they will disappear.Meanwhile, all the money you will save from not having to treat these diseases will now get funneled into research on infections.A century later, one really smart team will finally isolate the immortality mechanism of HeLa cells.You will take another century to redirect it’s vigor so that it will merely negate infections.You will take another half-century to find a way to create a new spot in the genome, for the genes that will code for the proteins that give HeLa cells their near invulnerability.You will finally have the genetic code for a system of cell repair that will isolate diseased or damaged cells and induce cell proliferation of surrounding healthy cells to match the death rate of faulty cells. You will finally have the tool to end all disease. And your nanobot delivery systems from the IDVP will still be around.You will start the MEM-HHP, the Moon-Earth-Mars Human Healing Program, to fix everyone forever. You’re going to find this easier to implement because high literacy levels coupled with a high development index will ensure rapid dissemination of the service.This time, 30% of the population will resist, insisting on embracing their original imperfect state. Civil unrest will break out, but it will be largely one-sided, because the only people needing treatment for injuries will be the people protesting the vaccine. Everyone else will simply self-heal. Over time, you will simply list these people in the genetic registry and let them be.Now your civilization will accelerate, without disease to hold it back.The population will explode. I mean literally explode. Every country on Earth will institute population restriction programs. A couple will be allowed to have one child, But if they want two, they will have to apply to the PACs.Could you elaborate on th…Pregnancy allocation courts. Since so many couples will be applying at the same time for a limited number of second-child positions, they will have to demonstrate their natural superiority over their competition. Panels of psychiatrists will have to be allocated to interview and assess each couple and rate them. Once the winners are allotted RTSPs, rights to a second pregnancy, OB-GYN teams will track the pregnancy (because each second pregnancy represents a huge investment on the parent’s part) and assist with the delivery. Pediatricians will track the growth and development of the children, as they would with all children.Family Medicine specialists will monitor their sectors and report in on their populations, and epidemiologists will track the trends. Imbalances will be adjusted for within a single generation by varying the RTSP spots available in a country.Sounds like heaven to me. So why would it go to hell?Ah. Because human nature. We’re always striving upwards, always wanting more. And you see the problem with wealth because it’s quantitative. But it’s harder to see with progress because progress is semi-quantitative. In fact,we usually tend to think of it in qualitative terms.Yes, but…Don’t interrupt me. I’m tired now, and I want to be done with this. Where was I? Ah! Qualitative terms. You see, major, when you create a population without disease or injury, you open up possibilities for them that didn’t exist before. Now they’re going to want to go places we couldn’t go and do things we never did. Or do the same old things with less. You will enter an age of artificial augmentation. Surgeons will start trying to incorporate prosthetic technology into human frames. People are going to ask for eyeballs with a zoom function, and comm-links in their ears.Surgeons will now have to find a way to place an incision that will hold, in a body that insists on repairing itself. And then immunological rejection will come into the picture. So the immunologists will go back to the drawing board all over, to find a way to make our cells accept foreign bodies.And one of them will go too far, and create immortality.It will be illegal of course, but that won’t stop people from buying it on the black market and using it. And catching them will be relatively easy, because they will not age over time. So they will have to make frequent visits to aesthetic surgeons…I beg your pardon. Did you say aesthetic surgeons?I think the word for them in your time, now, is plastic surgeons. By then their job will be mostly cosmetic corrections for the face, mostly. These aesthetic surgeons will now operate at the center of a black market that will artificially sculpt illegal immortal’s faces to imitate ageing.The law will crack down on this, of course. Except, how do you stop an immortal person capable of self-healing? You need a new generation of weapons. Mechanical injury would not work unless it is tremendously destructive, which is always a problem because of the collateral damage to innocent bystanders. No, what you will invent then will be toxic darts. Pharmacologists and pathologists will design toxins so powerful they can override even those cells. Quick and neat, eh?It’s incredible! Go on!People are going to want to leave, of course. It’s just that second earths, you know, Goldilocks planets are so far and few between, that inevitably some groups of rebels will have to slum it, on a planet too heavy/light, too bright/dark, too hard/soft, or even toxic. Anatomists, physiologists and biochemists will have to redesign us to adapt us to our new environments.And it will work. We will branch out as a species, some of us opting for denser bones, some for faster metabolisms, some for sulphur-based central metabolic cycles.This is crazy!<subject coughs>That is why I am here. To prevent the craziness for starting. Once you go down that road, there will be only one end.Which is?The place where we started, major.It’s that cliched story that never grows old. Boy meets girl, they learn to love each other despite their differences. Except that the differences in this case will kill them. The term you have for such a coupling: inter-subspecies coitus, won’t even apply here. In fact, we’ve stopped using the word species. We say <static> but I believe the closest word in your vocabulary would be “model”.Disease would re-enter the world. Worlds, rather. We’d be spread out all over the place, desperately trying to make sense of a reality we never imagined even in our wildest dreams. How do you think most of us would handle it?Mass suicide.Government-sponsored euthanasia. General physicians will be the last to die, of course, after euthanizing everyone else.My god.We god, rather. By then, we’d be gods: a thing we were never meant to be.<chair scraping>I’ve had enough. Show me to my quarantine quarter, major, please. And call a surgeon, my little toes are worse now. And tell him it isn’t an unusual presentation of Gout, that he just has to…<timestamp ends><static><beep>Well? You have your answer. Now don’t just stand there. Say something.Edit: I’m adding this a week after I wrote this answer. Came across this today. Breakthrough Tech: Scientists Use Swarms of Nanorobots to Precisely Target Cancer CellsFiction my ass.

What is your opinion about neuroscientist Kent Kiehl on the topic of psychopathy?

If I were only go based on his education and what he concentrates on, I might be inclined to roll my eyes. He was taught directly under Hare and only works in the prison system with violent criminals. He also uses the PCL-R as his assessment tool for those admitted into his studies.However, he actually does understand that most psychopaths are not criminals, and that those in prison are drastically different than the psychopaths that are not.Kent Kiehl: One of the biggest differences is that psychopaths are way more common than people believe. About one in 150 people will meet the stringent clinical criteria for the disorder. That means hundreds of thousands of them are out and about in the population. The majority of them don't commit violent crimes, but they lead this sort of disorganized, nomadic life, and they tend to eventually end up in some sort of trouble. Hollywood hasn't done a good job of portraying the average psychopath. For the most part, they've taken the extreme view, with the Hannibal Lecters and more sensationalized people like that. It's actually far more common and banal.This is a fair estimation. Compared to what neurotypicals think of as normal and settled in terms of life, I do not live that way at all. I change jobs when the fancy strikes me or a better offer comes along. I am not tied to one place to live, and have no problem staying in one place for a week, or a decade. Makes no difference to me. Also I don’t need to have personal connections or roots in my community. Sure, it might be useful, but it is certainly not something that I have a need for.Then this question and answer;WIRED: In the book you write that in two decades you've only come across a handful of people who scored 40 out of 40 on the psychopathy checklist (30 is commonly used as the psychopath cutoff. Regular folks tend to score around 4 or 5). What is it like to talk to a perfect psychopath?Kiehl: They are so fundamentally different. You leave the room knowing that you've just met someone who is extremely different, even different from other psychopaths. They are absolutely and completely free from conscience. They have this unbelievably flat affect that's really palpable when you look in their eyes.This is such an important distinction that a lot of people don’t seem to make, even those that claim psychopathy. I cannot count the number of times that a person writes on Quora about what a criminal they are, a 40/40 psychopath, but they really don’t comprehend that there are psychopaths, and then there are “above the snow line” or “A-Lister” psychopaths. That is a different animal entirely.Psychopaths that are in the general population are not “A-listers”. Psychopaths like that are fundamentally dangerous, just like anyone that is so criminally inclined that they view other humans as prey. The people making it into Kent Kiehl’s studies are not committing petty crime and beating up people in a bar. Those types cycle in and out of jail, and might be low to moderate functioning psychopaths, but the “above the snowline psychopaths? Yeah, they’re in prison, and with good reason. They are incapable of functioning in society for any length of time.Kent Kiehl also works with kids that are first time offenders with antisocial traits. This is one of the places that I disagree with him, and that is because he is terming their behavior as psychopathic, not antisocial. I dug into the Mendota Juvenile Treatment Center where this work is being conducted, and they do not specify what they are describing as psychopathic traits, only that they boys have a high number of offenses, and were likely to reoffend when they get out. That with treatment at the MJTC they had a significantly lowered likely of reoffending after the decompression therapy that they utilize.I will grant that the methodology of treatment, rewards over punishment, is what works with psychopaths, but they are juveniles. They are using the PCL-YV to assess these young men, and if you look at the traits;It has a lot of things that can be attributed to, brain not done growing yet, so go figure. This is one of the reason that I have an issue with psychopathy even being discussed prior to age twenty-five.Jordan Peterson was speaking about antisocial traits in an interview and he made the most interesting remark. He stated that a child that is conduct disordered by the age of four, the probability that they will be criminal by the age of fifteen to twenty is extremely high. However, conduct disordered is not psychopathic, and it can be caused by many things. So, I disagree with there being a PCL checklist for people under twenty-five as I think it is prejudicial, and I think those traits would be better termed conduct disordered, or antisocial as they can exist simply due to brain development not being complete.How do I know this? Because in the same study that they did on conduct disordered children that become criminals by the time they are teenagers to young adults, no matter what treatment thrown at them, there was no improvement. It was very frustrating to those reviewing the literature, there simply was nothing that they tried that made a difference.What did? They aged out of it. In fact there is a theory that the best way to treat a teenage/young adult criminal is to lock them up until they are twenty-seven. By then, most of them grow out of it. There is a drawback to this however, and that is the worst thing you can do with an antisocial teenager is to lock them up with other antisocial teenagers. You should expect failure if you do that. It’s all very interesting, and should be heavily noted that the neuroscience backs Peterson’s claims as well. The brain is considered mature around twenty-five, and this behavior drastically vanishes at that time with these antisocial teenagers.Well then, it wasn’t psychopathy then was it? It was brain development, which is not a disorder, it simply is the way that person is maturing. That isn’t to say that they shouldn’t be met where they are, and have proper guidance to get to the age that their brain is fully online, but let’s not deem them psychopathic, because that causes a lot of problems both for the understanding of psychopathy, and for those young men as they graduate into being an adult. Psychopathy is not something you want slung around your neck by any division of the government. Good luck getting rid of it.Kent Kiehl seems like a pretty reasonable guy. I think that he has some fundamental flaws in his approach, the largest of which would be his tutelage under Hare and the PCL-R as the assessment tool to get into the psychopath studies. In and of itself it is terribly flawed and basically is an excellent tool for identifying criminals. As it is only used in prisons or forensic hospitals, that makes it pretty pointless, not to mention redundant.I like that he is doing the brain scans, but I think he needs better criteria to enter into the studies. It would also be great if he would venture out of the prison system, and into the regular world and research functioning psychopaths. His is contributing to the myths of all being criminals when he exclusively studies and publishes things on criminals. The criminal psychopathic population is small, around thirteen percent of the overall psychopathic population.Maybe they have been studied enough, and it’s time to branch out a bit. We don’t study neurotypicals in prison, nor should we study psychopaths there. It is a self defeating exercise. You can only conclude that psychopaths are disproportionately criminally minded if you are exclusively studying criminals. It isn’t even a hard thing to understand. However, this tends to continue to be the case, and those that try to explore psychopathy in the noncriminal population are often met with disdain and even ridicule from other people in the field.This is due to the PCL-R being considered the gold standard in diagnostics, which over includes (even according to other researchers that tried to write a paper on this, and Robert Hare sued them for defamation of all things) antisocial traits. If that is how you are going to define psychopathy, it’s going to come across pretty badly to those that learn about it, they close their minds, and insist that all psychopaths are monsters.See, not too scientific. However, that is how it is currently. Kiehl of course contributes to this, which is something that I will disagree with him on, but he seems to have a more balanced view of psychopathy than most that were Hare’s students, so I will give him credit for that. Overall, cool that he is doing the brain scans. Not so much that they are all of criminals.Well done, but do better.What It's Like to Spend 20 Years Listening to Psychopaths for Sciencehttps://www.researchgate.net/publication/241727866_Critical_Issues_in_the_Assessment_of_Adolescent_Psychopathy_An_Illustration_Using_Two_Case_Studies/figures?lo=1&utm_source=google&utm_medium=organicCan Psychopaths Be Cured? | RealClearScienceFor the Jordan Peterson comments on antisocial teenagers, the clip begins at 3:08

Were you diagnosed with autism as an adult and how does an American adult go about getting the diagnosis?

I was diagnosed with autism as an adult. This is how I pursued it, in order of steps:So much research I thought my brain would explode.Online diagnostic tools, tests, checklists, ranging from extensive and serious to quick and dubious. I tried them all.Articles, professional opinions, definitions.Blogs by real life autistic people. This is what proved most helpful. I found that reading personal anecdotes and detailed first-person examples of the autistic experience made me feel understood in a way that was miraculous and uncanny.Talking about things with an autistic friend, comparing experiences, etc.I put things in writing. I found a massive checklist of characteristics for “women with Asperger’s” on the Everyday Aspergers blog. I copied and pasted the list into a document, color-coded my answers, and wrote descriptions and examples of each of the things I identified with. Most of the list was checked off.Extensive discussions with my therapist. Throughout this process, I started talking to my therapist about the possibility that I was autistic. It made a lot of sense to her. We continued to explore this and pretty much accept it over the next couple years. At this point, I still hadn’t sought official diagnosis. This questioning phase was the longest part for me, because I didn’t feel I needed an official determination. Also, to be perfectly honest, I hadn’t quite accepted myself. I had started to come out as autistic to select friends and family, but most people reacted negatively or completely dismissed me. In addition, I found myself having a negative/shame reaction to some of the autistic literature I read online. I am not proud of this fact but just being honest. A lot of the reason is that I kept reading a lot of things that were tailored toward children, and I felt a bit of defensiveness at the thought of being treated like a child. This is likely due to my history of being infantilized and not taken seriously. As a young adult, I wanted to espouse the whole “hey, I’m not a child!/I’m a serious, polished grown-up!/Don’t talk down to me like a kid or suggest toys to me!” thing. I wanted to find more adult resources.Questioning the questioning. Perhaps it was my own slight unacceptance of myself, or perhaps it was the revelation that I might have ADHD (which was a new thread I wanted to follow), but I started talking to my therapist about how I had no idea what, if anything, applied to me anymore. A lot of ADHD signs overlap with common Autism signs, and I started to get curious if maybe I wasn’t autistic after all.Referral for formal assessment. Finally, my therapist realized that I was at a place in my journey in which I would benefit from exploring all of this more deeply, this time with a specialist. She had a very solid recommendation for a colleague that was an autism and ADHD specialist who performed formal assessments in my general geographical vicinity. After extensive Googling of this person (and also because I highly trust my therapist), I decided I would like to pursue this.Setting an appointment with the specialist. I reached out to this specialist and inquired about cost, as that was definitely a huge factor for me. He told me his normal rate (super high and intimidating) but said he was also willing to slide a bit. By this point, we had already exchanged a few emails in which I’d told him more about me. He seemed genuinely interested in helping me get to the bottom of this and asked me what I could afford. I told him my maximum dollar amount (and apologized profusely that it was definitely less than what he deserved), and he graciously accepted. We set an appointment.Massive email vetting. I always prefer to get to know people via writing, as it is hard for me to open up verbally. Over the next several weeks, I sent lengthy emails about myself, and he responded to them very thoughtfully. This impressed me, since I’m used to getting the “um, please shut up” signs. This email vetting helped me become more comfortable with him, so that the first time I met him didn’t feel so sterile and scary.Appointment prep. Prior to the appointment, the specialist sent me intake and client info forms. I filled these forms out, using them as an opportunity to go into more detail about my autistic/ADHD signs.Assessment time. Assessment included a long-as-hell in-person appointment, many checklists, interview questions, emails, and even tests my friends had to take on behalf of me. The main formal tests administered for autism assessment were the Social Responsiveness Scale (SRS-2) Adult Self Report and the SRS Observer Report. For ADHD, it was the Connors’ Adult Attention Deficit/Hyperactivity Disorder Rating Scales (CAARS) Self Report and Observer Reports. We also had a group video/phone chat meeting with the specialist, my therapist, and myself. I believe my therapist and Joel also consulted amongst themselves, as I had previously signed release forms giving them permission to consult with one another about me. I appreciated this, because my therapist knows me really well, and I trusted her to fill in more blanks and give him further context.Diagnostic Impressions (aka “results”). About a month later, I received a 5-page written report with the specialist’s findings. Before the official report, he checked in with my therapist and I about his initial hunches. Basically, his response was “whoa hey, you're autistic as fuck, you glorious creature.” Ok, those weren’t his exact words, but he let me know very clearly that he strongly believed I was on the spectrum. My ADHD hunch wasn't wrong either though. To be specific, the findings he listed on the report were as follows:F84.0 Autism Spectrum Disorder, Level 3, Requiring Substantial SupportF90.2 Attention-Deficit/Hyperactivity Disorder, Combined PresentationAnd then two uncertain hypotheses that will need a closer look in the future (31.9 Unspecified Bipolar Disorder and R48.2 Ideomotor Apraxia).Recommendations. I was left with 6 major recommendations, including continued therapy, seeking services with my local regional center (for executive functioning assistance and other things), and several other things. One of his most steadfast, passionate recommendations was that I start embracing the Neurodiversity Paradigm, find self-empowerment, start being more open about my autism, and try to interact with more actually autistic community. His recommendations were spot on, and doing this last point has done wonders for my life.Bonus method: In order to be granted services from regional centers, they have to conduct extensive assessment on you first. Then, they determine if you qualify for their services. This is a great way (as in, non-expensive) to seek assessment, even if you aren’t granted services (not everyone gets them, because resources are limited). It takes a lot of patience to go through with that, though, and it was often highly triggering and taxing for me to go through that process. I encourage anyone doing this to try your best to push through it (and I don’t advocate pushing through most things; this is an exception, because it could potentially open up really helpful possibilities for autistic people in need of help).

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