Ucc Transcript: Fill & Download for Free

A2A. My GPA at Caltech was about a 3.2, and the average is above 3.5.How happy you can be with that depends a lot on your attitude and your goals. I transferred to Caltech from a community college, where everyone thought I was a genius. I realized quickly that I wasn't one of the geniuses at Caltech, and I didn't really enjoy pushing myself to become one. So I adjusted my goals. I treated every class I took as if it were on pass/fail. I tried to maximize learning things that I enjoyed, and sometimes ignored problems that I didn't find interesting.As part of that philosophy, I realized I could learn a lot of cool things from doing non-academic activities, too. They might not show up on your transcript, but they provide valuable experience in other ways. For example, I spent well over 100 hours on leading a Ditch Day stack, and it taught me a lot about myself and about organizing a group of people for a project.I also spent my senior year leading Bible studies for Caltech Christian Fellowship. That was a huge time commitment, approximately equal to taking another class. But as a Christian, my first priority in life is to know God better and to help others to know God better. It was definitely worth it, no question.Another part of having a healthy life is making close friends. I was almost always willing to put off work to go do fun things when I had the opportunity. Sometimes that was because I knew I could finish work later. Sometimes I just had more fun not studying.And sometimes, having a close friend means carving out time to help them deal with their own personal struggles. Depression is pretty common at Caltech, and while I never was in an official role as a UCC (Upper Class Counselors, who watch over each alley in the Houses), I did what I could to take care of the people I knew best.There have definitely been trade-offs. I switched to computer science for grad school instead of continuing in math, largely because CS is easier and provides a wider variety of options after graduating. Even still, I only was accepted to one grad school. But one is infinitely better than zero. So I'm mostly happy to be at UC Irvine now.It's interesting to see the reactions I get when I tell people I graduated from Caltech. It's usually something like, "Wow, you're super smart!", followed by "Why would you come here?" The real answer to that is this story. And while UCI isn't in the top tier, it's actually pretty highly ranked in CS. So I'm not disappointed.Looking back, how much would I change? There were times when I was just irresponsible, and I could have used my time better. But overall, I think I've been fairly successful at accomplishing my personal goals, even if they don't match what other people would expect. If I were to add anything, it's that I wish I had volunteered to be a UCC my senior year.For my future goals, it's still possible that I end up in academia, but that seems less likely all the time. I've never had a job out in the real world before, but I suspect I might enjoy that more. I have a few years while I'm in my doctorate program to figure that out, and I'll probably spend at least one or two summers as an intern at a software company. I might even apply to Quora...

At the DNA level, humans — like most eukaryotes¹ — have fairly inefficient genomes. It’s an interesting and clearly very workable coding system, but no; it doesn’t compress, and it doesn’t even garbage collect very often.The main function of the genome is the genes; segments of DNA that code for a protein. There are other functional elements beyond genes, but let’s get back to those later. A protein is a series of amino acids: little molecular building blocks. There are 20 “standard” ones, plus a few rare that I’ll skip over. This means that to store a gene, you need to store a long list of amino acids. There’s also two types of “control codes” — basically “start” and “stop”.There are four possible bases (A,T,G,C), so we clearly need more than one per amino acid. Two isn’t enough either (4*4=16), so DNA uses codons of three bases, allowing for 64 unique ones. A gene is simply stored as start, a long series of amino acid codes, and stop. There’s a couple of stop codes, actually; and very rarely you see an alternate start code. The stops codes are entirely unique, but the start codes are reused — inside a gene, they code for the amino acid methionine.Now, there’s clearly more possible codons than there are amino acids and control codes. They are all in use, though; as a primitive sort of redundancy encoding. The more common an amino acid is, the more codons will code for it: The idea is that if it a single base is mutated, it’ll still code for the same thing as before.When this DNA is actually used, it’s first copied off, then that copy is read and destroyed. The copying, transcription, creates a strand of mRNA (messenger RNA) that is complementary to the DNA: G becomes C, C becomes G, T becomes A, and A becomes … U, because RNA uses a slightly different molecule for that position. Thus, if you start out with AGG CTC, the mRNA will read UCC GAG. When talking about codons, it’s common to use the mRNA reading and not the DNA reading.Genes aren’t always a single stretch of codons. They can be split into blocks separated by unused DNA - we call the in-use blocks exons (since they are expressed) and the filler introns (since they are intragenic, “in the gene”, or intervening). The entire thing, introns and all, is first transcribed, and then the introns are edited out. However, this process can be modified: Sometimes, you get alternative splicing variants, where some of the exomes are dropped as well, as decided by proteins and other molecules that interfere with the transcription. This means that a single gene can code for multiple proteins — which means that while humans have around 20′000 genes, the number of possible protein variants are much higher. You could argue that this is a form of compression, or at least deduplication — though nothing is shared between genes.Oh, and all of this has ignored that huge chunks of DNA is noncoding and arguably pointless— copying errors have left huge chunks of repeats, there are old deactivated viruses and copies of genes in there, there are “mobile elements” that, again, are basically copying errors — and you could probably live fine without most of it.There are also functional things in the noncoding DNA outside the genes, though - a few thousand bases before most genes there’s a promotor region: a stretch of DNA that fits with (and attracts) the protein machinery that does the transcriptions. There are regions that can hold “blocking” molecules to stop transcription, there are miRNA regions (that get transcribed, but the mRNA itself is the active part and never gets converted to a protein), and all sorts of other weird and wonderful badly understood things. There is also the entire study of epigenetics - modifications that aren’t in the DNA code itself; things like methyl groups binding to DNA in certain positions, hindering (or sometimes promoting) transcription of certain genes or exomes. That’s kind of outside the point here, though.In total, this means that a gene without any introns, coding for three phenylalanines chained together (way shorter than any real protein) could look something like this (with the noncoding region shortened way down):DNA TATAAxxxxxxxxTAC AAA AAA AAA ATCxxxxxxxx mRNA AUG UUU UUU UUU UAG  pro- non- Start Phe Phe Phe Stop non-  motor coding coding I’d call it “not compressed at all”, except for the funky alternative splicing system.1: Eukaryots are animals, plants, fungus … basically anything that isn’t a bacteria or archea. Bacteria use the same DNA encoding as everyone else, but are under more pressure to make it efficient. This means that they do things like having multiple copies of important genes, so they can transcribe multiple copies at once; they have almost no noncoding DNA, they don’t have introns at all, they group multiple genes together to get transcribed as a block, and some bacteria go so far as to have genes overlapping each other to save space.

Exon:-The section of a eukaryotic gene containing genetic information in the synthesis of partial sequence of a gene product (polypeptide).Many eukaryotic genes are composed of exons and introns, the latter playing no part incoding amino acid sequence of the gene product. In course of transcription, the total part of the gene is first transcribed into pre mRNA. In the further stage, known as “processing” or “post transcriptional modification”. The nature of mRNA require for translation is formed, i.e., introns are excised from the pre m RNA, & the exons containing the genetic information are placed together in correct sequence.Sex controlled Inheritence:-Inheritence of characters which are expressed differently (Quantitavely or Qualitavely) in males and females.Mutation:- The spontaneous or experimentally induced qualitative or quantitative alteration of genetic material. The following types of Mutation are listed separately: gene mutation, chromosomal mutation; genome mutation, Plasmon mutation, plastid mutation.Mutant:- The individual organism, which as a result of mutation, shows characteristic visible or measurable differences from the parent or wild type organism. The minimal change necessary for the generation of a mutant is the alteration of a single nucleotide in the genome.Gene Mutation:-A spontaneous or experimentally induced alternation in the molecular structure of a gene, which modifies the encoded genetic information, thereby producing a new allele. Gene mutation differs from genome mutation and chromosomal mutation. Gene mutations are often point mutation, arising from the change of a single nucleotide pair of DNA of a gene. In a point mutation, only a single base pair is affected: in a transition, the purine base is replaced by other purine base (guanine replaced by adenine or vice versa) and the pyrimidine base replaced by the other pyrimidine base (cytosine by thymine or vice versa); in a transversion a purine is replaced by a pyrimidine and the pyrimidine replaced by a purine. In both cases, the member of nucleotides residues remains unchanged but part of the sequence (affecting a single triplet) is altered. Deletion or insertion of nucleotide within a gene results in a frameshift mutation.In a frameshift mutation, transcription still commence at the same site on the DNA, and proceeds unchanged to the point where nucleotides have been inserted or deleted. Thus the number and sequence of nucleotides has changed. These changes are preserved during transcription and translation so that the final translation is altered. For example, m RNA sequence UUU, CUC, CCA, CAG is translated into the peptide chain Phe-leu pro-glu; deletion f a single nucleotide eg., the first U produces the sequence UUC, UCC, CAG, GAG,…………………, which would be translated as Ser-ser gln.The point mutation that changes the codon for one amino acid into the codon for a different amino acid is called a missense mutation. For the new codon is the termination codon, the change is known as non-sense mutation. Since the genetic code contains only three termination codons, most single base replacements result in missense rather than non sense. Many codons are synonymous that the point mutation may have no effect on the encoded amino acid; such mutation (eg., a change from CUU to CUG both of which go for leucine) are known as silent mutation. A silent mutation is different from a neutral mutation, which does goes an alteration of a translation , but the alteration does not prevent the from birth its normal biological function.