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Why is iodine-131 injected into the blood stream of a patient with an overactive thyroid gland, instead of irradiating the thyroid gland externally?
Probably the cost of treatment, and insurance company delimiters which places the I-131 as the preferred method.There is a growing concern about the treatment causing brain tumors later in a treated persons life, and some leukemias as well.Long-term follow-up studies have indicated an increased incidence of second primary malignancies after I-131 therapy. Of the two major recent reports, Rubino et al. (1) reported an increased risk of solid tumors and leukemia with increasing cumulative activity of I-131 administered with an excess absolute risk of 14.4 solid cancers and 0.8 leukemias per GBq of I-131 and 105 person-years of follow-up, as well as a relationship between I-131 and bone and soft tissue, colorectal, and salivary gland cancers. Brown et al. (2) reported an overall increased risk of second primary malignancies. The review by Sawka et al. of the above two articles reported a significant but small increased relative risk of a second primary malignancy in patients treated with I-131 with a 2.5 relative increased risk of leukemia. No significant increased risk of the following cancers was observed: bladder, breast, central nervous system, colon= rectum, digestive tract, stomach, pancreas, kidney, lung, or melanoma of the skin (3)I take a personal interest in this as a close family friend was treated to I-131 in the late 70’s and came down with a leukemia45 years later. While pausing for treatment for it at Stanford H., it was discovered he had a brain tumor as well, so treatment wasn’t pursued.————————————-1. Rubino C, de Vathaire F, Dottorini ME, Hall P, Schvartz C, Couette JE, Dondon MG, Abbas MT, Langlois C, Schlumberger M 2003 Second primary malignancies in thyroid cancer patients. Br J Cancer 89: 1638–1644.2. Brown AP, Chen J, Hitchcock YJ, Szabo A, Schrieve DC, Tward JD 2008 The risk of second primary malignancies up to three decades after the treatment of differentiated thyroid cancer. J Clin Endocrinol Metab 93:504–515.3. Sawka AM, Thabane L, Parlea L, Ibrahim-Zada I, Tsang RW, Brierley JD, Straus S, Ezzat S, Goldstein DP 2009 Second primary malignancy risk after radioactive iodine treatment for thyroid cancer: a systematic review and meta-analysis. Thyroid 19:451–457.
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Review<html><head><title>Cycling Tours</title><link href="cyclingstyle.css" rel="stylesheet"><style></style></head><body><nav id="list"><ul><li><a href="#">Trip Prep</a></li><li><a href="seminars.html">Seminars</a></li><li><a href="reviews.html">Reviews</a></li><li><a href="#">FAQ</a></li><li><a href="#">Destinations</a></li><li><a href="#">Ask Us</a></li><li><a href="aboutus.html">About Us</a></li></ul></nav><header><h1><a href="#">Cycling Tours</a></h1><img src="images/bicyclebanner.jpg" alt="Bicycle Banner" ></header><h2>Reviews</h2><form id="review1" action="https://csunix.mohawkcollege.ca/tooltime/showit.pl" method="post" ><fieldset id="tripReview"><legend>Trip Review</legend><div><label for="trip"></label><select id="trip"><option value="B.C. Mountains">B.C. 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Can enough photons be condensed collided together in a small space into a larger particle like an electron?
What Dr Jachollkowski is trying to say involves virtual photons. There are ‘real’ photons, like those that come from a light bulb, and can live indefinately and travel to an indefinate endpoint, then there are ‘virtual photons,’ which unlike real photons, possess mass, and only live a few wavelengths.Virtual photons are what the electromagnetic force is. When two magnets come close together, they exchange virtual photons. However, the existence of virtual photons is a mathematical entity, nonetheless, they exert a ‘real’ force.However, they possess integer spin =1, meaning they remain bosons. However/however, unlike massless photons, massive virtual photons cannot be stacked a mile high like in a LASER. In the information theory that would be a violation of the Beckenstein-Verlinde relationship that I’ve explained so many times I’m just going to say ‘look up my old answers.’ Essentially, you can only stack massive information up as high as:will allow. That was the entire ‘Information Paradox.’ You can only stack it so high was the result, the query was, can you make it go away?If you read the article at LHC that Dr Jachollkowski provided, you can see that two hadrons (i dont’t think it makes mention of leptons) pass close enough, their electromagnetic fields will produce virtual photons. However, this does not imply that the opposite is true, that you can produce particles by stacking up virtual photons. Although most things in QM are reversible, i don’t think this is one of them.Most importantly, there is no way to manipulate virtual photons in such a way as to pack them together like you suggest. They fade out too quickly.The claim of colliding virtual photons to generate particles is a subjective observation, an interpretation that requires ‘belief’ as much as math. first, you have to believe that virtual photons are real entities, and not mathematical constructs of field physics. after you get past that cognitive belief barrier, then you have to believe that two interacting fields (not actually the fields, but the holes in the fields) can produce a wave function which a particle physicist calls a particle. After that, you then have to ‘believe’ that the appearence of an electron-positron pair resulted from virtual photon interactions because you can’t see anything else in proximity to cause that to happen, but you can backtrack to a pair of hadrons passing each other at relativistic speeds, scraping EM fields.I don’t know. In my way of thinking, I group particle physicists in with biologists. They have a name for everything, but can’t seem to figure out how they work.1. 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Shift of an electron interferencepattern by enclosed magnetic flux. Phys RevLett 5:3–5.10. Moriyasu K. 1983. An Elementary Primer forGauge Theory. Singapore: World Scientific.11. Berry MV. 1984. Quantal phase factors accompanyingadiabatic changes. Proc R Soc (London) A 392:45–57.12. Aharonov Y, Anandan J. 1987. Phase change duringcyclic quantum evolution. Phys Rev Lett 58:1593–1596.13. Tycko R. 1987. Adiabatic rotational splittings andBerry’s phase in nuclear quadrupole resonance. PhysRev Lett 58:2281–2284.14. Suter D, Chingas GC, Harris RA, Pines A. 1987.Berry’s phase in magnetic resonance. Mol Phys61:1327–1340.15. Suter D, Mueller KT, Pines A. 1988. Study of theAharonov-Anandan quantum phase by NMR interferometry.Phys Rev Lett 60:1218–1220.16. Zwanziger JW, Koenig M, Pines A. 1990. Non-Abelianeffects in a quadrupole system rotating aroundtwo axes. Phys Rev A 42:3107–3110.17. Furman GB, Kadzhaya IM. 1993. Bloch-Siegertshift and Berry phase effect in nuclear magnetic resonance.J Magn Reson A 105:7–9.18. Steffen M, Vandersypen LMK, Chuang IL. 2000.Simultaneous soft pulses applied at nearby frequencies.J Magn Reson 146:369–374.19. Kayanuma Y. 1997. Stokes phase and geometricalphase in a driven two-level system. Phys Rev A55:R2495–R2498.20. Schwinger J. 1948. On quantum electrodynamicsand the magnetic moment of the electron. Phys Rev73:416–417.21. Weinberg S. 1995. The Quantum Theory of Fields.Vol. I—Foundations. Cambridge: Cambridge UniversityPress. pp 452–457 and 472–498.22. Zee A. 2003. Quantum Field Theory in a Nutshell.Princeton and Oxford: Princeton University Press.23. Greiner W, Schramm S, Stein E. 2002. QuantumChromodynamics, 2nd ed. Berlin: Springer.336 ENGELKEConcepts in Magnetic Resonance Part A (Bridging Education and Research) DOI 10.1002/cmr.a24. Pich A. 1995. Quantum Chromodynamics. LectureNotes. arXiv:hep-ph/9505231v1. 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Ultra-small-sample molecular structure detectionusing microslot waveguide nuclear spin resonance.Proc Natl Acad Sci USA 104:9198–9203.44. Busch P, Lahti PJ, Mittelstaedt P. 1996. The Theoryof Quantum Measurement, 2nd ed. Berlin:Springer.45. Braginsky VB, Khalili FY. 1992. Quantum Measurement.Cambridge: Cambridge University Press.46. von Neumann J, Grundlagen der Quantenmechanik.1955. Mathematical Foundations of QuantumMechanics. Princeton, NJ: Princeton University Press.47. Birkhoff G, von Neumann J. 1936. The logics ofquantum mechanics. Ann Math 37:823.48. Feynman RP. 1982. Simulating physics with computers.Int J Theor Phys 21:467–488.49. Deutsch D. 1987. Quantum theory, the ChurchTuringprinciple and the universal quantum computer.Proc R Soc Lond A 400:97–117.50. Deutsch D. 1989. Quantum computational networks.Proc R Soc Lond A 425:73–90.51. Preskill J. 1997. Quantum Information and Computation.Lecture Notes. Pasadena: California Instituteof Technology.52. Stolze J, Suter D. 2004. Quantum Computing.Weinheim: Wiley-VCH.53. Zeilinger A. 2000. Quantum computing: quantumentangled bits step closer to IT. Science 289:405–406.54. Jeener J, Henin F. 1986. Fixed bound atom interactingwith a coherent pulse of quantized radiation:Excitation and short time behavior. Phys Rev A34:4897–4928.55. Jeener J, Henin F. 2002. A presentation of pulsednuclear magnetic resonance with full quantization ofthe radio frequency magnetic field. J Chem Phys116:8036–8047.56. Hoult DI. 1989. The magnetic resonance myth ofradio waves. Concepts Magn Reson 1:1–5.57. Hoult DI, Bhakar B. 1997. NMR signal reception:virtual photons and coherent spontaneous emission.Concepts Magn Reson 9:277–297.58. Hoult DI, Ginsberg NS. 2001. The quantum originsof the free induction decay signal and spin noise.J Magn Reson 148:182–199.59. Hoult DI. 2004. The Quantum Origins of the NMRSignal: A Paradigm for Faraday Induction. Physicsin Canada Conference.
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