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Caption: “””Papa Smurf’ Paul Karason, Colored Blue by Colloidal Silver, Walks On.“”””” The man who turned a Smurf-like blue after taking colloidal silver for dermatitis has died, though not from his self-administered medical regimen.Paul Karason, who changed color over the course of 15 years while using the preparation of silver particles suspended in liquid, died on September 24 in Washington state. He had suffered a heart attack, contracted pneumonia and had a stroke, his estranged wife, Jo Anna Karason, told Today. The 62-year-old was a heavy smoker with heart problems, the New York Daily News reported, and had had a triple-bypass five years ago.Karason administered his silver doses himself, according to Today, using electrolysis to produce the colloidal preparation. He took it both internally and rubbed it on his face to treat a skin condition; the latter act, he believed, is what made him change color.Silver is known to do this because of the way it reacts with light, and that is part of what got it banned by the Federal Drug Administration (FDA) in 1999. The antibacterial properties the metal possesses were not as potent as those in penicillin, which was developed in the 1930s, according to Today.“The silver collects in the skin and other organs and does not dissipate,” Today said. “Karason is blue for life.”His 15 minutes of fame were bracketed by two Today appearances, the first in 2008 when he initially appeared on Today to discuss his blueness, and the second in 2009 when he showed up for an update on his curious hue. Karason had a sense of humor about the condition, known as argyria””””, ‘Papa Smurf’ Paul Karason, Colored Blue by Colloidal Silver, Walks On .- - - -******** A VERY, VERY long time. For the rest of your life.Silver in health care: antimicrobial effects and safety in use.(Lansdown AB1., Author information1Imperial College Faculty of Medicine, Charing Cross Hospital, London, UK. [email protected])“””” Abstract ~ Silver has a long and intriguing history as an antibiotic in human health care. It has been developed for use in water purification, wound care, bone prostheses, reconstructive orthopaedic surgery, cardiac devices, catheters and surgical appliances. Advancing biotechnology has enabled incorporation of ionizable silver into fabrics for clinical use to reduce the risk of nosocomial infections and for personal hygiene. The antimicrobial action of silver or silver compounds is proportional to the bioactive silver ion (Ag(+)) released and its availability to interact with bacterial or fungal cell membranes.Silver metal and inorganic silver compounds ionize in the presence of water, body fluids or tissue exudates. The silver ion is biologically active and readily interacts with proteins, amino acid residues, free anions and receptors on mammalian and eukaryotic cell membranes. Bacterial (and probably fungal) sensitivity to silver is genetically determined and relates to the levels of intracellular silver uptake and its ability to interact and irreversibly denature key enzyme systems.Silver exhibits low toxicity in the human body, and minimal risk is expected due to clinical exposure by inhalation, ingestion, dermal application or through the urological or haematogenous route. Chronic ingestion or inhalation of silver preparations (especially colloidal silver) can lead to deposition of silver metal/silver sulphide particles in the skin (argyria), eye (argyrosis) and other organs.These are not life-threatening conditions but cosmetically undesirable. Silver is absorbed into the human body and enters the systemic circulation as a protein complex to be eliminated by the liver and kidneys. Silver metabolism is modulated by induction and binding to metallothioneins. This complex mitigates the cellular toxicity of silver and contributes to tissue repair. Silver allergy is a known contra-indication for using silver in medical devices or antibiotic textiles””””, Silver in health care: antimicrobial effects and safety in use. .

Urology devices is a surgical specialty that deals with the treatment of conditions involving the male and female urinary tract and the male reproductive organs of the certain conditions such as cancer of the urinary tract, urologists may need to work in conjunction with oncologists or radiotherapists The authors of the report have used easy-to-understand language and uncomplicated statistical images but provided thorough information and detailed data on the global Urology Surgical Devices market.Global Urology Devices Market Research Report 2019The research sources and tools that we use are highly reliable and trustworthy. The Report offers effective Guidelines and direction for players to Secure Position of Device urology. Earlier the laser system was restricted to nephrolithiasis, nowadays, it is a valuable tool for the treatment of urology diseases, such as BPH prostate cancer and kidney cancer. This development is expected to have a positive impact on the overall market growth. The Global Urology Devices market analysis is provided for the international markets including development trends, competitive landscape analysis, and key regions development status. Development policies and plans are discussed as well as manufacturing processes and cost structures are also analyzedKey Players of Urology Devices market Olympus, Boston Scientific, Medtronic, Teleflex, Karl Storz, Richard Wolf, Coopersurgical, Coloplast, Conmed, Stryker, Cook Medical.Major Regions Covered in this Report are: Urology Devices Analysts Expert are Expert in Converging Japan, India. The U.S., Europe and North America with accurate Statistical and Regional Clafication we provide you. An analysis of the technical barriers, other issues, cost effectiveness affecting the Urology Devices Market. Determining the opportunities, future of the Urology Devices and its restraints becomes a lot easier with this report.The Comprehensive Report of Urology Devices Market includes a competitive landscape and an analysis of Porter’s Five Forces model for the market. The study encompasses a market attractiveness analysis, wherein all the segments are benchmarked based on their market size, growth rate, and general attractiveness. For each manufacturer covered, this report analyzes their Urology Devices manufacturing sites, capacity, production, factory price, revenue and market share in global market.Market Segmented by Type: Instruments, Consumables and Accessories, Segment by Application, Hospitals and Clinics, Dialysis Centers, Conclusions.The report offers the market growth rate, size, and forecasts at the global level. In addition as for the geographic areas: Latin America, Europe, Asia Pacific, North America, and Middle East & Africa also analyses. It provides the global market size of the main players in each region. Moreover, the report provides knowledge of the leading market players within the Urology Device market.know more about Introspective Market Research

Global Urology Imaging Systems Market Expected to Reach US$ 441.6 Mn by 2026The latest market report published by Credence Research, Inc. “Urology Imaging Systems Market - Growth, Future Prospects, and Competitive Analysis, 2018 - 2026” the urology imaging systems market was valued at US$ 302.4 Mn in 2017 and expected to reach US$ 441.6 Mn by 2026 at a CAGR of 4.1% during the forecast period from 2018 to 2026.Market InsightsThe global urology imaging systems market shows dynamic progress during the forecast period from 2018 to 2026. Major factors such as the increasing burden of target diseases on a global scale, improved product commercialization, increasing private funding to support new product development, evolution of digital platforms, and the formation of new diagnostic centers are driving the market growth.Additionally, new launch of advanced portable imaging systems along with growing demand for 3D-4D devices is driving the market. Additionally, partnerships with diagnostics centers by medical technology companies internationally and product technology expansion in emerging nations are factors driving the growth of the urology imaging systems market.Sample Request - Credence ResearchWorldwide rising prevalence of urinary incontinence, fecal incontinence, chronic anal fissure, constipation, perineal pain, hindgut dysfunction, and urinary retention are anticipated to fuel the growth of the market. Other factors include increasing ambulatory care, progression in the digital platforms, and utilization of advanced imaging systems in the diagnostic centers segment.Additionally, growing partnerships with clinics, effective patient diagnosis along with enhanced workflow efficiency will drive the demand during the forecast period. However, the high cost of on platform urology imaging systems, limited diagnostic services, less awareness, and affordability concerns for new imaging systems for multiple applications are limiting the growth of the urology imaging systems market globally.Inquiry Before BuyingKey Market Movements:• Globally, the urology imaging systems market will grow with a CAGR of 4.1% during the period from 2018 to 2026• Increasing adoption in the portable segment is gaining traction in the market• Evolution from 2D to 3D clinical diagnostics along with integration of healthcare infrastructure cloud-based solutions will drive the growth prominently• Asia Pacific and Europe are the key regions in the global market due to established distribution networks of local manufacturers along with higher patient pool with urological disorders• Major players in this vertical are GE Healthcare (General Electric Company), Esaote SpA, Shenzhen Mindray Bio-Medical Electronics Co., Ltd., BK Ultrasound, Siemens Healthineers, Philips Healthcare, Verathon Inc., LABORIE, Samsung, Echo-Son, ECM Echo Control Medical SAS, Ampronix, Toshiba Medical, Fujifilm Sonosite, Hitachi, Ltd. and othersTOC :Chapter 1. Preface ......Chapter 2. Executive Summary ......Chapter 3. Global Urology Imaging Systems Market: Market Dynamics and Future Outlook ......Chapter 4. Global Urology Imaging Systems Market, by Product Type, 2016 – 2026 (US$ Mn)4.1. Overview4.2. Standalone Ultrasound Systems4.3. Portable Ultrasound Systems4.4. Fluoroscopy Based Systems (Conventional Radiology)Chapter 5. Global Urology Imaging Systems Market, by End User, 2016 – 2026 (US$)5.1. Overview5.2. Hospitals5.3. Diagnostic Centers5.4. Ambulatory Surgical Centers5.5. ClinicsChapter 6. Global Urology Imaging Systems Market, by Geography, 2016 – 2026 (US$ Mn)6.1. Overview6.2. North America Urology Imaging Systems Market Analysis, 2016 – 20266.2.1. North America Urology Imaging Systems Market, by Product Type, 2016 – 2026 (US$ Mn)6.2.2. North America Urology Imaging Systems Market, by End User, 2016 – 2026 (US$ Mn)6.2.3. North America Urology Imaging Systems Market, by Country, 2016 – 2026 (US$ Mn)6.2.3.1. U.S.6.2.3.2. Canada ......Chapter 7. Company Profiles7.1. GE Healthcare, Inc.7.1.1. Business Description7.1.2. Financial Information (Subject to data availability)7.1.3. Product Portfolio7.1.4. Key Developments7.2. Esaote SpA7.3. Shenzhen Mindray Bio-Medical Electronics Co., Ltd.7.4. BK Medical Holding Company, Inc.7.5. Hitachi, Ltd.7.6. Siemens Healthineers7.7. Philips Healthcare7.8. Verathon Inc.7.9. LABORIE7.10. Samsung7.11. Echo-Son7.12. ECM Echo Control Medical SAS7.13. Ampronix7.14. Toshiba Medical7.15. Fujifilm Sonosite7.16. Hitachi, Ltd.7.17. Olympus Corporation ......