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How do I prepare for the RBI grade B DSIM exam?

RBI Grade B officer in the Department of Statistics and Information or RBI Grade B DSIM post is applicable for candidates who possess a Master's Degree in Statistics / Mathematical Economics / Mathematical Statistics / Statistics & Informatics / Econometrics or Applied Statistics & Informatics with a certain percentage of marks that differ from one category to another. RBI Grade B DSIM officer work will deals mainly with collection, compilation, analysis and interpretation of data on banking, corporate and external sectors.The exam will take place in three stages -Phase I- Paper 1- Objective type questions on Statistics- 120 min - 100 marksPhase II - Paper 2: 180 min 100 marks and 3: 90 min 100 marks - Descriptive typeInterview - 75 marksNow the preparation part and books to follow becomes very important, as a small carelessness can cost you a big penalty. Well I may be not the write person to tell you how to prepare because aspirants who are preparing for this exam have lot of information more precise and accurate than me. My write up is just based on some research and opinion. So some books which i find you can look for-Probability and Statistics for Engineering and the Sciences - Jay DevoreProbability and Statistics - Degroot and SchervishFundamentals of Mathematical - Gupta KapoorFundamental of Applied Statistics - Gupta KapoorFundamental of Statistics Vol. 1 and 2 - Gun Gupta DasguptaTheory and Methods of Survey Sampling Book - Parimal MukhopadhyayNow how to prepare. Then the solution to this lies with in you. You know what your flaws and strengths are. Where you lack and what you need to catch up. So decide your own study plan and be consistence with it but leave room for flexibility as peer need arises.

Which book should I prefer in Class 9 for the Maths CBSE?

Especially For MathI will suggest , don’t solve so many textbook that you heard either from your classmates or teachers in your school like : RD SHARMA, TOGETHER WITH, RS AGGARWAL etc. Go through one book and try to solve two or more times throughout the book, so that you learn key concept and memories related formulas .I had chosen RD SHARMA because it contains all NCERT problems and some previous papers with two or three sample papers. I think this book is sufficient for practice and for scoring good marks in CBSE 9th or even in CBSE 10th and its solutions are also easily available RD Sharma Class 9 Solutions.If you have enough time try to solve previous year question papers or latest sample papers issued by CBSE from ncerthelp.com , topperlearning.com or mycbseguide.com etc.If you preparing for school level MATH competitive examination like RMO, IMO, IOM, NIMO, NTSE etc . You don’t need to solve school level text books : RD SHARMA, TOGETHER WITH, RS AGGARWAL etc. You can easily score 90% + by preparing for these exams or can increase it to 95%+ by solving previous year question papers. You may say that Boards syllabus is a subset of these olympiads syllabus. So, if you prepare for these , it will be best.For ScienceFirst of all go through NCERT books to know syllabus, learn basics and their applications then refer to reference books to get more advance information . Solve questions of inside and outside of text content from NCERT . Always try to focus on key concepts .I will suggest choose books for physics, chemistry, biology by S CHAND for theory , together with numerical problems for class 9th and previous year question papers to get extra information and practice .If you preparing for school level SCIENCE competitive examination like NSEJS, NLSTSE, SLSTSE, IOS, NSO, SSTSE etc . Check out their official website to get more information and search corresponding examination books, past year papers and recent sample paper on Google.FOR Social ScienceI think NCERT textbook is enough for acquiring knowledge and scoring goods marks. So, read it carefully and mark important points itself .For notes and previous years question papers go throughmycbseguide.comwww.learncbse.inncerthelp.com etc.FOR Hindi & EnglishJust read the NCERT text books and solve their questions .For extra practice and to know what types of question asked checkout Golden Guide and for IEO (International English Olympiad) go to the official website .Best of luck !!

How does the Zika virus harm a man if he plans to conceive a child in the near future?

There is as yet no direct evidence of Zika harming a man's reproductive capacity, i.e., no evidence as yet that Zika renders a man either temporarily or permanently sterile. However, multiple reports document presence of Zika in semen. A Zika-infected man could thus potentially transmit this virus during intercourse. Pregnancy resulting from such intercourse is one way for a fetus to get infected. A man's Zika infection could thus potentially harm his future child.Data suggest Zika is present in semen and could be sexually transmitted: As of April 2016, there are at least 5 official reports of Zika virus in semen of infected menCase #1 (1, 2): Long before Zika became a global news story, in 2008 two Colorado State University researchers, Brian D. Foy and Kevin C. Kobylinski, were collecting mosquitoes in a southeastern Senegalese village called Bandafassi for a malaria study. While there, both reported being bitten many times. They returned to Colorado on 24 August, 2008. ~Five days later both became ill with extreme fatigue, fever, headaches and rash on torso, swollen and painful wrists, knees and ankles, symptoms suggestive of an infection. Foy also had genital pain (from undiagnosed prostatitis?), painful urination and possible hematospermia (bloody semen). 10 days later, on 3 September, Foy's wife showed similar clinical symptoms including chills, malaise, extreme headache, hypersensitivity to light and muscle pains. Yet, their 4 children remained healthy and unaffected.Foy, his wife and Kobylinski recovered within a week though with lingering joint pains. Tests showed the two researchers, but not Foy's wife, had serum anti-Dengue antibodies. Dengue's another Flavivirus with symptoms similar to Zika. Foy and Kobylinksi had been vaccinated against another flavivirus, Yellow fever, which could explain their anti-Dengue antibodies. Antibodies raised against Dengue, Yellow fever or Zika cross-react because these related viruses contain shared antigens. No definitive answer forthcoming for what had infected them, Foy stored all three frozen serum samples.By chance when Kobylinksi went back to Senegal a year later, he met Andrew Haddow, a University of Texas Medical Branch (UTMB), Galveston medical entomologist working on Zika. Coincidentally Haddow's grandfather was one of three scientists who originally isolated Zika virus from a rhesus monkey in the Zika forest near Entebbe, Uganda in 1947 (3). After Kobylinksi returned to the US in December 2009, he and Foy sent all three frozen serum samples to Haddow to test for Zika.All three samples contained anti-Zika antibodies. How did Foy's wife get infected with Zika? Colorado doesn't harbor Zika transmitting mosquito species. In fact, at that time Zika was a little known flavivirus with no report of it in the US. As well, the timing of Foy's wife's infection didn't fit the scenario of a mosquito that 1st bit her infected husband and then bit her. Zika transmitted from human to mosquito needs to complete a 2 week life cycle within it before it can infect another human. Foy's wife fell ill within 10 days of his return. However, Foy and his wife had had vaginal sexual intercourse shortly after his return from Senegal and before he showed clinical symptoms. This strongly implied sexual transmission.Case #2 (4): In 2013, French Polynesian researchers found live Zika virus in the semen of a 44 year old Tahitian man. The man reported having fatigue, low-grade fever, and joint pains for ~3 days in early December 2013. ~ 8 weeks later, he had symptom recurrence. ~ 2 weeks post-recurrence, he noticed hematospermia and only then sought treatment. Authors collected blood and semen samples from him 3 days apart as well as an urine sample during the 2nd visit. Observing hematospermia only in the 1st semen sample, they detected Zika virus in semen and urine, not in blood. In urine they only detected it by Reverse transcription polymerase chain reaction (RT-PCR) but not by culture. OTOH, they detected it in both semen samples by both RT-PCR as well as culture. Virus levels were high in semen and the culture results suggested presence of live virus, even >10 weeks after symptoms first appeared.Case #3 (5): In February 2016, Texas health officials reported Zika in a person after they had sex with someone who'd recently returned from Venezuela.Case #4 (6): UK researchers found Zika in a man's semen 62 days after he first had fever. In this case the 68 year old man had fever, fatigue and rash one week after returning from the Cook Islands. Serum samples collected 3 days after fever onset were negative for Dengue and Chikunguniya viruses by RT-PCR. Tests also didn't detect anti-Dengue or -Chikunguniya antibodies. OTOH, samples were positive for low levels of Zika virus by RT-PCR. Authors collected convalescent phase serum, urine and serum samples. Only semen samples were positive for Zika virus by RT-PCR 27 and 62 days after patient 1st had fever. They were also positive for anti-Zika antibodies.Case #5 (7): In January 2016, a 32 year old man was diagnosed with Zika infection at Toulouse University Hospital in Toulouse, France. Two days after he returned from Brazil and French Guyana, he developed symptoms suggesting an flavivirus infection. RT-PCR test detected Zika, not Dengue nor Chikunguniya. Two weeks post-diagnosis, authors again took blood, urine and semen samples. Virus loads were semen > urine > plasma. In fact, authors estimate semen viral load was ~100,000X that of blood or urine even >2 weeks after symptoms began. Virus present in semen was live because authors could get it to replicate in cell cultures.Implications of Finding Zika Virus in SemenFlaviviruses like Dengue, Chikunguniya, Yellow fever are similar to Zika in that they're transmitted by the bite of infected Aedes mosquitoes. However, they'e not known to be sexually transmitted. What's being observed about Zika in this regard is thus truly novel and it means approaches to contain it can't simply borrow from the play book developed and used for those other flaviviruses. Instead, it'll be much harder, necessitating both vector-borne control measures as well as measures commonly used for sexually transmitted diseases. Meantime, several critical issues about this aspect need urgent answers.Is this virus present in the semen of every Zika-infected man? If not, what risk factors predispose to its presence in semen: age, health status, past infection history especially for Zika or other flaviviruses, genetics are some obvious factors to consider. Since these case studies found Zika in semen from men aged in their 30s to their 60s, a broad age range, age may be a less important factor.Zika in semen implies infected testes. If this is so, how long does such infection last? And what risk factors predispose to likelihood and duration of testes infection?How long post-infection is Zika virus present in an infected man's semen? Virus is found in blood only during the acute phase (1 to 2 weeks). Available data suggests it lasts longer in semen but how much longer?Is a Zika-infected man with hematospermia (bloody semen) more likely to harbor Zika in semen and transmit it? Both Cases 1 and 2 reported genital pain (from undiagnosed prostatitis?) and hematospermia.Since majority of Zika infection is asymptomatic, viral presence in semen represents a potentially enormous reservoir. It's thus necessary to estimate how long after Zika infection a man carries the risk of transmitting it during intercourse.So what precautions should a man living in or traveling to Zika-prevalent regions take?“If I was a man and I got Zika symptoms, I’d wait a couple of months before having unprotected sex,” said Scott Weaver, director of the Institute for Human Infections and Immunity at the University of Texas Medical Branch in Galveston and an expert on the virus. “If my wife was of childbearing age, I’d want to use protection, certainly for a few weeks.”(8).Bibliography1. Foy, Brian D., et al. "Probable non-vector-borne transmission of Zika virus, Colorado, USA." Emerg Infect Dis 17.5 (2011): 880-2. http://wwwnc.cdc.gov/eid/article/17/5/pdfs/10-1939.pdf2. Sex After a Field Trip Yields Scientific First. Science, Martin Enserink, April 6, 2011. Sex After a Field Trip Yields Scientific First3. Dick, G. W. A., S. F. Kitchen, and A. J. Haddow. "Zika virus (I). Isolations and serological specificity." Transactions of the Royal Society of Tropical Medicine and Hygiene 46.5 (1952): 509-520. Zika Virus (I). Isolations and serological specificity4. Musso, Didier, et al. "Potential sexual transmission of Zika virus." Emerging infectious diseases 21.2 (2015): 359. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313657/pdf/14-1363.pdf5. Zika Infection Transmitted by Sex Reported in Texas. The New York Times, Donald G. McNeil Jr., Sabrina Tavernise, Feb 2, 2016. Zika Infection Transmitted by Sex Reported in Texas6. Atkinson, Barry, et al. "Detection of Zika virus in semen." Emerg Infect Dis 22.5 (2016). Emerging Infectious Disease journal7. Mansuy, Jean Michel, et al. "Zika virus: high infectious viral load in semen, a new sexually transmitted pathogen." Lancet Infect Dis 16.405 (2016): 00138-9. https://www.researchgate.net/profile/Guillaume_Martin-Blondel/publication/297597948_Zika_virus_high_infectious_viral_load_in_semen_a_new_sexually_transmitted_pathogen/links/56e1d44c08aebc9edb19ca07.pdf8. The New York Times, Donald G. McNeil Jr., Jan 25, 2016. Zika Virus: Two Cases Suggest It Could Be Spread Through SexThanks for the A2A, Diana Tan.

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