2015-2016 Immunization Record: Fill & Download for Free

I can show both that vaccines do in fact protect you AND that they are worth the risk. How? With free online statistics data and 5th grade math.The Vaccine Adverse Event Reporting System is a cooperative program for vaccine safety of the Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA). VAERS is a post-marketing safety surveillance program, collecting information about adverse events (possible side effects) that occur after the administration of US licensed vaccines. This online database provides a nationwide mechanism by which these reports may be analyzed and made available to the public. The data are updated monthly and include reports received through the last Friday of the previous month. See the Vaccine Adverse Event Reporting System (VAERS) web site for more information.No one thinks that vaccines are 100% safe. No drug is. This is why there is an entire system devoted to watching how vaccines function after they make it to market and check for safety concerns. The records of this system go back to 1990 and you can search it using a wide variety of different fields such as vaccine used, symptoms, whether they recovered, the severity of the reaction, known allergies and other medical conditions prior to vaccination, etc. It can even make tables, charts, and maps for you. For such a handy system, you would think more anti-vaxxers would reference it instead of making up conspiracies about how “Big Pharma is suppressing the truth and using vaccines as population control/making money by keeping people sick”.I did a search for all reports related to any type of influenza vaccine between January of 2014 and December of 2015.20,428 reported casesOut of those cases: 1,179 ( 5.77%) were seriousData from the CDC says:148.1 million (95% CI 146.6–149.7 million) people vaccinated against seasonal flu during July 2014 through May 2015 among the civilian, non-institutionalized U.S. population.Flu Vaccination Coverage, United States, 2014-15 Influenza Season (I added the bold)So, .014% of people who were vaccinated had some form of adverse reaction and only .0008% of those reactions were serious. If you want to know the details, you can easily put in a search for yourself: The Vaccine Adverse Event Reporting System (VAERS) RequestThat looks pretty safe to me, but does it work?CDC’s end-of-season influenza vaccine effectiveness (VE) estimates for the 2014-2015 season were presented to the Advisory Committee on Immunization Practices (ACIP) on June 24, 2015. CDC’s adjusted overall VE estimate against influenza A and B viruses for all ages was 23%. The adjusted VE estimate against influenza A (H3N2) viruses for all ages was 13%.Reduced protection against influenza A (H3N2) viruses for the 2014-2015 season was attributed to the fact that more than 80% of circulating influenza A (H3N2) viruses analyzed at CDC were different or “drifted” from the recommended influenza A (H3N2) vaccine virus….Laboratory analysis of circulating flu viruses indicated that most of the influenza A (H3N2) viruses were antigenically or genetically different than the influenza A (H3N2) vaccine virus. This is probably why there was reduced vaccine effectiveness against those drifted influenza A (H3N2) viruses. However, the vaccine worked well against about one-third of circulating influenza A (H3N2) viruses that were similar to the recommended vaccine virus and against influenza A (H1N1) and influenza B viruses.What You Should Know for the 2014-2015 Influenza SeasonWell no. It looks like the vaccine was a bad match for this year. So what about the next year?CDC’s end-of-season influenza vaccine effectiveness (VE) estimates for the 2015-2016 season were presented to the Advisory Committee on Immunization Practices (ACIP) on June 22, 2016. CDC’s adjusted overall VE estimate against influenza A and B viruses for all ages was 47%. The overall VE against A(H1N1)pdm09 was 41% and the overall VE against influenza B was 55%. This data is consistent with VE observed during previous seasons when vaccine viruses and circulating viruses were similar. These vaccine effectiveness estimates were derived from data collected from the U.S. Flu VE Network from November 2, 2015, through April 15, 2016…Was this season's vaccine a good match for circulating viruses?Yes. Laboratory data show that most of the circulating flu viruses were like the viruses recommended for the 2015-2016 influenza vaccines.What You Should Know for the 2015-2016 Influenza SeasonA much better match. Choosing the right vaccines for the virus is difficult since you are actually making predictions. Sometimes you get it right, sometimes you don’t. Medicine isn’t perfect and you are dealing with a “live” virus population after all. Things get complex.In this case, 50% effectiveness against a disease that used to kill people by the millions with only a .014% chance of an adverse reaction and only a .0008% chance that it will be serious? It doesn’t take a lot of skill in math to see that vaccines are a pretty good choice when comparing costs with benefits. Even if you are unlucky and the vaccine is only 13% effective, it isn’t like you are taking a big risk. However, you should do the obvious thing and check for possible allergies or other potentially complicating factors beforehand. Apart from that, the benefits of vaccines very clearly outweigh the risks, especially when you consider that there are many people who cannot be vaccinated (e.g. babies and the those with impaired immune systems) and you being vaccinated helps prevent diseases getting to them through you. Contributing to herd immunity is sort of a public duty.

The check point inhibitors are taking cancer treatment by storm in 2015. These are antibodies that unleash the immune system against cancers. After decades of frustratingly slow and unrewarding work by immunologists, they've come up with something big that works in a lot of different cancers and in a lot of patients. These drugs breakdown the camouflage that cancer cells use to protect themselves from immune detection and release the brakes on the immune system.Breakthrough Immune Checkpoint Inhibitors Revolutionize Oncolgoy TreatmentsBreakthrough Cancer Drugs, At Last?New therapies raise hope for a breakthrough in tackling cancer2015 saw a record approval for use in a wide variety of dangerous cancer situations including metastatic melanoma, metastatic lung cancer, metastatic kidney cancer. 2016 will see approval in metastatic head and neck cancer and possibly some lymphomas the year after.

In cricket, records are broken more frequently than in other sports since there are huge number of them. However, some records have been comfortably immune and may not be broken.Highest test score: Sri Lanka 952/6.No team has ever come close to the mammoth score of 952. Most of the other big scores have been very long ago. The closest any team came after Sri lanka scored the total in 1997 was Pak’s 765, almost 200 runs fewer.Most Fours and Sixes in ODI career.Most Fours:Sachin: 2016Jayasuriya: 1499Most Sixes:Sahid Afridi: 351Jayasuriya: 270(Not comparing with Jayasuriya, he is 2nd on the list both the times)Both Sachin and Afridi are comfortably ahead in fours and sixes records. Someone breaking their record should be able to hit fours/sixes at a rapid rate for a long peroid of time and should start playing at a very young age like they both did.Most Career Hundred:Sachin: 100Ponting: 71Another record that I can bet on is Sachin’s 100 international centuries. Kohli is closing on in ODI, but far behind overall with 47 international centuries.Highest partnership in test:624 run partnership between and Sanga and Jayawardene vs South Africa is solid one too. South Africa lost the series in Sri Lanka in 2005 and were unbeaten overseas after that for a decade until falling to spin in India in 2015.Largest victory in test.579 runs defeat itself is very huge one, and adding inning to that would be infinitely huge.Don Bradman’s average of 99.94 looks very improbable too and stood for a long time. However Adam Voges career was flirting with that number for quite some time. A series of low score in over 10 innings bought that down to 61 before he retired. Since, he was already 37 years old had he retired some months earlier his test average would have challenged 99.94.Adam Voges bettered Sachin’s long standing record of 497 without being dismissed. He went well past it with 614 runs but his dismissal not only ended the streak but also caused his average to dip below 100 to 99.64.Fastest ODI century:If Afridi’s 37 ball century stood for 17 years then ABD’s 31 ball century might stand very long as well. 5 ball is a huge difference. There are lot of player capable of scoring 17,18 ball fifty, but should carry on with more pace even longer till 100.Slowest fifty:Maraj’s 53*(155) vs South Africa is one of the major record that have gone unnoticed.Mural’’s Improbables:If Murali’’s 800 test wicket is tough to break, even harder is his 67 five wicket hauls. His 4 consecutive 10 wicket hauls (twice) looks completely immune too.Most runs in test series:Bradman’s mountainous 974 might not see any climbers. Grame Smith scored 621 runs in first 3 inning of 5 test series in England in 2003. But his rest 6 innings extended his total to 714 for the series.image source: espncricinfo