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Who are the best pediatric rheumatology vasculitis specialists with expertise with treating non-responsive Kawasaki disease?

Don't know if they're the best. However, the following research and publish prolifically on the topic:Jane C. Burns, Professor of Pediatrics, Director of Kawasaki Disease Research Program at University of California, San Diego (UCSD): Center for Immunity, Infection & Inflammation: Jane Burns, MDAriana H. Tremoulet, Associate Director of the Kawasaki Disease Research Center at UCSD: Adriana Tremoulet, M.D.Alessandra Franco, Associate Adjunct Professor, UCSD: Error | UCSD ProfilesThanks for the A2A, Jay Wacker.

What are some of the universities/Research Institutes in India, where stem cells is one of the main areas of research?

There are few universities where few researchers are working on different stem cells . Some institutes I am mentioning as below:The Centre for Stem Cell Research (CSCR), a unit of the Institute of Stem Cell Research and Regenerative Medicine (inStem), Bengaluru, has been established as a collaboration between inStem, the Department of Biotechnology, Ministry of Science and Technology, Government of India and the Christian Medical College, Vellore. CSCR is supported by the Department of Biotechnology of the Ministry of Science & Technology, Government of India. Welcome to CSCR, The Centre for Stem Cell Research, A Unit of InStem2. Indian Institute of ScienceIndian Institute of Science, Bangalore 560 012, KarnatakaEmail:[email protected]: www.iisc.ernet.in/Research Areas: Biochemistry, ecological sciences, microbiology & cell biology, molecular biophysics, molecular reproduction, development & genetics.3. Centre of Excellence for Stem Cell Research,Stem Cell Facility at All India Institute of Medical SciencesNew DelhiEmail: [email protected]: www.aiims.ac.in/4. Nichi-In* Centre for Regenerative Medicine (NCRM) is an institute affiliated with the Tamilnadu Dr. MGR Medical University in India. NCRM is the first Indo-Japan joint venture institute in the country, carrying out research, training and clinical applications-protocol development in regenerative medicine, with emphasis on Stem cells, Progenitor cells and autologous adult cells with regenerative capability.: NCRM : : Nichi-In Centre for Regenerative Medicine(NCRM), Chennai, India An Indo-Japan venture on stem cell therapeutics tissue engineering,FEAT,Fujio-Eiji Academic Terrain, stem cells PhD, TPRM courses5. Centre for DNA Fingerprinting and DiagnosticsCDFD, Bldg. 7, Gruhakalpa, 5-4-399/B, Nampally, Hyderabad - 500 001.Email: [email protected]: www.cdfd.org.in/Research Areas: Automated genome analysis, bacterial genetics, cancer biology, cell biology & gene expression, computational biology, computational & functional genomics, immunology, mammalian genetics, molecular genetics, molecular oncology, molecular virology, structural biology, transcription, developmental neuroscience and drosophila genetics.6. Stem Cell Research at LV Prasad Eye IntstituteHyderabad, Andhra Pradesh, IndiaEmail: [email protected]: www.lvpei.org/LVPEI is a World Health Organization Collaborating Center for Prevention of Blindness. Equipped with cutting-edge technology and distinguished professionals in the field of Eye careL V Prasad Eye InstituteL V Prasad Eye Institute7. National Centre for Cell SciencesNCCS Complex, Ganeshkhind, Pune 411 007, MaharashtraEmail: [email protected]: www.nccs.res.in/Research Areas: Cell biology, molecular biology, immunology, parasitology, hybridoma technology, tissue banking & tissue engineering, regenerative biology, virology (HIV), cancer biology, diabetes, cryobiology transplantation, gene therapy.8. Centre for Cellular and Molecular Biology.Hyderabad. Center for Stem Cell Research, Vellore;9. National Brain Research Centre, New Delhi;10. National Centre for Cell Science, Pune.11. Center For Stem Cell Science, HyderabadCenter for Stem Cell Science12. Institute for Stem Cell Biology and Regenerative Medicine (inStem)An autonomous research institute in Bangalore, dedicated to the study of stem cell biology and regenerative medicine research. inStem is funded by DBT and well-supported, with access to facilities at both National Centre for Biological Sciences (NCBS) and Centre for Cellular and Molecular Plateforms (C-CAMP). Together these three institutions serve as part of the Bangalore Bio-cluster. The institute is also the umbrella organization for three initiatives: inStem itself, the Center for Stem Cell Research (CSCR) located at CMC Vellore, and an Extramural Program in Stem Cell Research (EPiSTEM), a funding initiative for support of stem cell research nationwide.Research and Academics: 1. Centre for Brain Development and Repair (CBDR), 2. Centre for Cardiovasular Biology and Disease (CCBD), 3. Centre for Chemical Biology and Therapeutics (CCBT), 4. Centre for Inflammation and Tissue Homeostasis (CITH), 5.Technologies for the Advancement of Science (TAS), 6.Programme on Adult Stem Cell Potency (SCP)13. National Institute for Research in Reproductive Health (NIRRH), formerly known as Institute for Research in Reproduction is a premier research institute of the Indian Council of Medical Research (ICMR). NIRRH, Mumbai14. National Institute of Immunology, New DelhiReproduction, Development & Cell BiologyAsok MukhopadhyayAneeshkumar A.G.

What is the history of Asperger’s?

The history of autism & Asperger syndrome1798 — French physician Jean-Marc Gaspard Itard described Victor of Aveyron, a young boy who was found after being isolated in the woods for 11 years, as being socially withdrawn in addition to having language and intellectual disabilities. He recognized Victor as being developmentally different from other children his age. Itard’s description of Victor’s tendencies would later be formally characterized as autistic (Itard, 1932).[1]1887 — British physician John Langdon Down, the first to describe Down’s syndrome, researched mental retardation. His description of developmental retardation describes individuals who would be classified as having autism today.[2]1908 — Swiss psychiatrist and eugenicist Eugen Bleuler coins the term autism to describe a subset of schizophrenic patients who were especially withdrawn and self-absorbed.[3]1925 — Soviet child psychiatrist Grunya Sukhareva was the first to publish a detailed description of autistic symptoms in Russian in 1925 and in German a year later. She initially used the term schizoid psychopathy (meaning of the time: eccentric psychopathology) but later replaced it with autistic psychopathy (pathological avoidant psychopathy) to describe the clinical picture of autism.[4]1927 — French psychiatrist Eugène Minkowski, a student of Bleuler, further defined autism as the “trouble generator” of schizophrenia.[5]1943 — American child psychiatrist Leo Kanner studied 11 children with difficulties in social interactions, difficulty in adapting to changes in routines, good memory, sensitivity to stimuli (especially sound), resistance and allergies to food, good intellectual potential, difficulties in spontaneous activity, echolalia (the propensity to repeat words of the speaker).[6]1944 — Austrian pediatrician, medical theorist, and medical professor Hans Asperger describes a “milder” form of autism now known as Asperger syndrome. The cases he reported were all boys who were highly intelligent but had trouble with social interactions and specific obsessive interests.[7]1949 — American child psychiatrist Leo Kanner observed a small sampling of children from well-educated families. Due to the limited sample size and selectiveness of the population used, Kanner made the erroneous statement that children with autism were more likely to be born into highly intellectual families. During this study, he began calling the mothering style as “cold”, and thus these mothers were later referred to as refrigerator mothers.[8]1950s — Austrian psychoanalyst Bruno Bettleheim claimed that autism was an emotional disorder that developed in some children due to psychological harm brought upon them by their mothers. Bettleheim wrote multiple books and appeared in magazines as well as prime time television discussing the theory.[9] The theory was wrong however, and after his suicide in 1990 it became apparent that he had no psychoanalytics credentials.[10]1952 — The first Diagnostic Statistical Manual (DSM) categorized autism as a childhood subtype of schizophrenia (American Psychiatric Association, 1952) though autism was eventually separated from schizophrenia.[11]1964 — American research psychologist, writer, and lecturer Bernard Rimland, who was a father of a son with high-functioning autism, presented the first solid argument that autism is a biological condition, and has nothing to do with the parent–child relationship. He founded the Autism Society of America for parents to have a voice against the Refrigerator Mother Theory.[12]Results of a pubmed search for articles containing the word “Asperger” in the title, published between 1976 and November 2015. (Image source: A Concise History of Asperger Syndrome: The Short Reign of a Troublesome Diagnosis)1977 — Research on twins finds that autism is largely caused by genetics and biological differences in brain development.[13]1980 — Infantile autism is listed in the Diagnostic and Statistical Manual of Mental Disorders (DSM) for the first time[14]; the condition is also officially separated from childhood schizophrenia.1980s — The work of Hans Asperger was translated to English and published internationally, meaning his work now came to prominence, and Asperger syndrome was starting to become known.1987 — The DSM replaces infantile autism with a more expansive definition of autism disorder, and includes a checklist of diagnostic criteria. Norwegian-American clinical psychologist and professor Ole Ivar Lovaas publishes the first study showing how intensive behavior therapy can help children with autism.[15]1994 — Asperger syndrome and PDD-NOS are added to the DSM, thus expanding the spectrum of autism conditions with high-functioning variants.[16]1998 — A study published in The Lancet suggests that the measles-mumps-rubella (MMR) vaccine causes autism, although these findings were quickly debunked, and no causal link has been found.[17]2000 — Vaccine manufacturers remove thimerosal (a mercury-based preservative) from all routine childhood vaccines, due to public fears of its alleged cause of autism.2008–present — ASD is found to be caused by the interaction of genes and environmental factors, as genes statistically associated with autism are emphasized to be important in inflammation and in innate immune pathways, including pathways for susceptibility to asthma. Acetaminophen (paracetamol) is thought to have an increased risk for autism.[18][19][20][21]Image credit: Vitamin D Wiki2009 — The U.S. Centers for Disease Control and Prevention (CDC) estimates that 1 in 68 children have autism spectrum disorders[22], up from 1 in 150 in 2002. The CDC notes that the increase stems at least in part from improved screening and diagnostic techniques.2013 — The DSM-5 generalizes all autism conditions to a diagnosis of autism spectrum disorder (ASD). As such, Asperger syndrome is no longer considered a separate condition.[23]And below is (part of) the history of autism as described above, in images.Image source: NerdGraphFor more information on (high-functioning) ASD, have a look at: Embrace ASDA blog about quantitative- and qualitative research on autism, by Natalie Engelbrecht and Martin Silvertant.Footnotes[1] https://pdfs.semanticscholar.org/6ed8/57e5d256422f23815ca2eab358f3b51d22ac.pdf[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677584/[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080676/[4] Sukhareva—Prior to Asperger and Kanner[5] http://www.easewellbeing.co.uk/PDF_Downloads/Urfer-2001-Phenomenology-and-Psychopathology-of-Schizophrenia-the-views-of-Eugene-Minkowski.pdf[6] https://www.google.nl/url?sa=t&rct=j&q=&esrc=s&source=web&cd=3&cad=rja&uact=8&ved=0ahUKEwjF6Z6Qs_HVAhVCZVAKHe98DWUQFgg8MAI&url=https%3A%2F%2Fsimonsfoundation.s3.amazonaws.com%2Fshare%2F071207-leo-kanner-autistic-affective-contact.pdf&usg=AFQjCNFiuOyKOnJWyTDerAtlKzethmMrPQ[7] Die „Autistischen Psychopathen” im Kindesalter[8] APA PsycNET Login[9] Infantile Autism and the Birth of the Self: Infantile Autism and the Birth of Self: Amazon.co.uk: Bruno Bettelheim: 9780029031407: Books[10] Genius Or Fraud? Bettelheim's Biographers Can't Seem To Decide[11] DSM I | DSM Library[12] Bernard Rimland, 78, Scientist Who Revised View of Autism, Dies[13] INFANTILE AUTISM: A GENETIC STUDY OF 21 TWIN PAIRS[14] An Evaluation of DSM-III Criteria for Infantile Autism[15] Dr. Ole Ivar Lovaas | Pioneer of Applied Behavior Analysis (ABA)[16] A Concise History of Asperger Syndrome: The Short Reign of a Troublesome Diagnosis[17] Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association[18] Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder[19] Similarities in features of autism and asthma and a possible link to acetaminophen use[20] Use of acetaminophen (paracetamol) during pregnancy and the risk of autism spectrum disorder in...[21] The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism[22] Facts About ASDs[23] DSM-V: What Changes May Mean

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