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What is the most horrifying scientific theory that many people do not know about?
This is a fairly recent scientific development that I believe most people haven’t heard about:In November last year, a Chinese researcher He Jiankui of Southern University of Science and Technology of China claimed he helped make the world’s first genetically edited babies using the CRISPR technology, sparking widespread backlash from medical and bioethics experts.(CRISPR/Cas9 — or CRISPR — is a tool that allows researchers to attempt to control which genes get expressed; to delete undesirable traits and, potentially, add desirable traits more quickly and precisely than ever before. )While the work has not been published and verified in a peer-reviewed journal, he claimed at a conference in Hong Kong that he had altered the DNA of twin girls born in December (at the embryo stage during IVF) to make them HIV-resistant. He deleted two genes whose deletions could have a health benefit: CCR5, without which people can’t get HIV and PCSK9, which leads to low levels of bad cholesterol and a much lower risk of heart disease.CRISPR is error prone and can introduce new and potentially harmful mutations. Kiran Musunuru, a gene-editing scientist at the Perelman School of Medicine in Pennsylvania, saw the genetic readouts on the embryos and recognized that the girls may be made up of a mosaic of differently edited cells. Others have commented that the work hasn’t been sufficiently investigated to confirm whether it worked or was safe. Other scientists have remarked that the work was sloppy and not done correctly.This bombshell announcement has sparked intense debate about whether there should be CRISPR babies at all. What if CRISPR could be used to replace broken genes? What if it could be used to create humans with superhuman qualities, ushering a new era of genetic inequality? What if CRISPR introduces new, unknown undesirable health issues?He’s clinical trial was halted but the government seems ambivalent about the way forward. Meanwhile, scientists at Harvard Universities are pressing ahead with sperm DNA-editing with the hope to create IVF babies with reduced risk for Alzheimer’s disease. It looks like scientists have opened a Pandora’s box and unsure what to do with it.
What are some less known facts about Shakuntala Devi?
Shakuntala Devi, also known as the “Human Computer” had humble beginnings. Here are a few unknown facts about her.Her father was a circus artist. And she was just 3 years old when her father discovered her memorizing power as she was memorizing sequences of playing cards.Shakuntala Devi used to perform on the streets along with her father where she solved complex math problems without any formal education.At 6 years old, she showcased her abilities at the University of Mysore, Annamalai University and other varsities in Vishakapatnam and Hyderabad.on October 5th, 1950, BBC Host Leslie Mitchell gave her a complex math problem and Shakuntala Devi solved it in seconds but the answer did not match. Later it turned out that the original answer was wrong and Shankutala Devi had actually given the correct answer.She famously calculated the 23rd root of a 201 digit number in 50 seconds at the Southern Methodist University, Dallas. The US Bureau had to write a special program on the UNIVAC 1101 to check her answer.She was also a writer. Her book, The World of Homosexuals (1977) is the first comprehensive study of homosexuals in India. She also wrote on other topics such as astrology and memorizing power.Google commemorated her birthday via this doodle.
What colleges have you applied and been accepted into?
A lot of people have been asking me about this in comments and messages, so I decided to address it in an answer.As you may know, I am 17 and will be graduating high school at the end of May. I made my final decision and committed to my favorite school about 3 days ago. For reference, I applied to every school as a computer science major.I was accepted to:University of Massachusetts, AmherstUniversity of Maryland, College ParkSan José State UniversityUniversity of California, Santa CruzUniversity of California, Santa BarbaraUniversity of Washington, SeattleI was waitlisted at:Northwestern UniversityUniversity of California, San DiegoUniversity of California, IrvineUniversity of Southern CaliforniaDuke UniversityAnd I was rejected from:University of California, BerkeleyUniversity of California, Los AngelesUniversity of North Carolina, Chapel HillColumbia UniversityCarnegie Mellon UniversityAnd finally, after a lot of deliberation and research, I committed to…Purdue University in West Lafayette, Indiana.I visited the campus earlier this week and I cannot express how excited I am to start. Yes, the winters can be brutal and it takes almost a day to get there from where I live, but it’s the perfect place to start this next chapter of my life. It’s going to be difficult to maintain my GPA as a comp sci major, but if I work hard, take advantage of everything the school has to offer and keep myself engaged I can go really far.Boiler up!As a word of caution for this year’s high school juniors- when I took a tour, the CS department head mentioned that Purdue accepted almost 95% of their students through early action. Just something to consider when you start applying to schools this fall!Edit: I had a 3.8 gpa and a 1570 SAT. I took 4 APs last year and 4 this year, but I think something that hurt me was that I only took APCS this year and not last year.
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